Genome wide association analysis for iron and zinc content in wheat landraces
Material type:
TextPublication details: 2014Description: 1 pageSummary: Nutritional security is the second most important thrust after food security in global agricultural research. Bio-fortification of staple food crops such as wheat with micro-nutrients can help greatly to meet global nutritional demands. Iron (Fe) and Zinc (Zn) deficiency are important concerns for cereal rich diets, particularly in the developing nations. Enhancing bio-availability of the micro elements Fe and Zn through increasing their content in wheat grain is a low-cost, highly effective strategy. Low genetic variation in cultivated wheat for Fe and Zn content is a limiting factor which hampers efforts made by breeders to increase Fe and Zn content in the grain of modern wheat cultivars. Identifying several alleles with small effects followed by their pyramiding to farmer adapted elite wheat cultivars can be an alternative approach. Screening of a set of 1180 bread wheat landraces from Mexico and Iran was carried out for Fe and Zn content. Further these landraces were genotyped through genotype-by-sequencing (GBS). Structure analysis and PCA of these landraces revealed three sub-populations, two sub-populations among Iranian and one sub-population of Mexican landrace. Marker trait associations were performed through GLM and MLM approaches. Preliminary analysis revealed three major loci (on chromosomes 2B, 3A and 5B) for Zn content and two loci (on chromosomes 2A and 7A) for the Fe content. Further validation of results across environments is underway. Identified regions could be useful for in depth genomic analysis to understand the genetic basis of Fe and Zn content in wheat grain.
| Item type | Current library | Collection | Call number | Status | Date due | Barcode | Item holds | |
|---|---|---|---|---|---|---|---|---|
| Conference proceedings | CIMMYT Knowledge Center: John Woolston Library | CIMMYT Staff Publications Collection | CIS-7474 (Browse shelf(Opens below)) | Available |
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Abstract only
Nutritional security is the second most important thrust after food security in global agricultural research. Bio-fortification of staple food crops such as wheat with micro-nutrients can help greatly to meet global nutritional demands. Iron (Fe) and Zinc (Zn) deficiency are important concerns for cereal rich diets, particularly in the developing nations. Enhancing bio-availability of the micro elements Fe and Zn through increasing their content in wheat grain is a low-cost, highly effective strategy. Low genetic variation in cultivated wheat for Fe and Zn content is a limiting factor which hampers efforts made by breeders to increase Fe and Zn content in the grain of modern wheat cultivars. Identifying several alleles with small effects followed by their pyramiding to farmer adapted elite wheat cultivars can be an alternative approach. Screening of a set of 1180 bread wheat landraces from Mexico and Iran was carried out for Fe and Zn content. Further these landraces were genotyped through genotype-by-sequencing (GBS). Structure analysis and PCA of these landraces revealed three sub-populations, two sub-populations among Iranian and one sub-population of Mexican landrace. Marker trait associations were performed through GLM and MLM approaches. Preliminary analysis revealed three major loci (on chromosomes 2B, 3A and 5B) for Zn content and two loci (on chromosomes 2A and 7A) for the Fe content. Further validation of results across environments is underway. Identified regions could be useful for in depth genomic analysis to understand the genetic basis of Fe and Zn content in wheat grain.
Genetic Resources Program|Global Wheat Program
English
Lucia Segura
I1705725|INT2731|INT0368|INT1422|INT3466|INT3049|INT3098
CIMMYT Staff Publications Collection