000			02850nam a22002537a 4500
001			G94569
003			MX-TxCIM
005			20171106163737.0
008			121211s ||||f| 0 p|p||0|| |
020			_a978-979-1159-41-8
040			_aMX-TxCIM
090			_aCIS-6135
100	1		_9861 _aMahuku, G. _gGlobal Maize Program _8INT2822 _uProceedings of the Asian Regional Maize Workshop, 10; Makassar (Indonesia); 20-23 Oct 2008
245	0	0	_aMaize pathology in Asia: _b opportunities and challenges for breeding disease-resistant maize
260			_aMexico, DF (Mexico) _bCIMMYT : _c2010
300			_ap. 361-366
520			_aMore than 12% of maize productivity is lost to diseases annually in Asia. Sources of resistance to several important diseases have been identified in advanced CIMMYT germplasm but the genetics of resistance is poorly understood. Disease resistance in maize is reported to be conditioned by both major (qualitative) genes and minor (quantitative) genes or quantitative trait loci (QTL). To date, 437 quantitative disease resistance loci or dQTL, 17 major resistance genes and 25 resistance gene analogs (RGAs) associated with resistance to 11 maize diseases have been described in a few of these sources. QTL mapping studies conducted in maize thus far have provided information on the genetic architecture of disease resistance including the number, location and action of chromosomal segments conditioning the trait. The availability of the maize genome sequence offers new opportunities for a detailed understanding of the organization and architecture of disease resistance, fine mapping of QTL, validating candidate genes and identifying effective molecular markers to improve disease resistance. However, full exploitation of genomic approaches and information to develop and release maize cultivars more resilient to diseases will only be possible through (i) a deeper integration of genomic approaches with conventional breeding methodologies; (ii) a capacity to reliably and accurately phenotype diseases on a large scale; and (iii) a sound multidisciplinary knowledge of the biochemical and physiological processes determining crop yield and its stability under different disease stress regimes. A major emphasis for the Asian region will have to include the collaborative evaluation of promising sources of resistance for specific traits using standardized protocols that would allow harmonization of disease phenotypic data for use in identifying the most promising resistance genes, validating molecular markers liked to effective dQTL and major resistance genes and incorporation of the most promising sources in improvement activities.
536			_aGlobal Maize Program
546			_aEnglish
593			_aLucia Segura
594			_aINT2822
700	1		_aZaidi, P.H.|Azrai, M.|Pixley, K.V. _eeds.
942			_cPRO _2ddc
999			_c7988 _d7988