000			03291nab|a22004457a|4500
001			69065
003			MX-TxCIM
005			20250722112349.0
008			20257s2025|||| -uk||p|op||||00||0|eng|dd
022			_a2096-5362
024	8		_ahttps://doi.org/10.1186/s42483-025-00345-1
040			_aMX-TxCIM
041			_aeng
100	0		_aYue Zhang _919133
245	1	o	_aQTL mapping for leaf rust resistance in a recombinant inbred line population from the cross of wheat cultivars Zhongmai 578/Jimai 22
260			_aUnited Kingdom : _bBioMed Central Ltd., _c2025.
500			_aPeer review
500			_aOpen Access
520			_aLeaf rust is a highly destructive disease that poses a significant threat to both the yield and quality of wheat. Identification of genetic loci can aid in enhancing leaf rust resistance in wheat breeding. In the present study, 262 recombinant inbred lines derived from a cross between Zhongmai 578 and Jimai 22 were used to map leaf rust resistance loci using the Wheat 50K single-nucleotide polymorphism (SNP) array across four environments. Four quantitative trait loci (QTL) on chromosomes 2B (2), 5B, and 7B were identified through composite interval mapping, designated QLr.caas-2B.1, QLr.caas-2B.2, QLr.caas-5B, and QLr.caas-7B, respectively, explaining 3.7%-19.6% of the phenotypic variances. The resistance alleles at QLr.caas-2B.1, QLr.caas-5B, and QLr.caas-7B originated from Zhongmai 578, while that at QLr.caas-2B.2 came from Jimai 22. Both QLr.caas-2B.2 and QLr.caas-5B overlapped with loci previously reported, whereas QLr.caas-2B.1 and QLr.caas-7B are likely to be new loci. Two kompetitive allele-specific PCR (KASP) markers, KASP-QLr.caas-2B.2 and KASP-QLr.caas-5B, were proven to be significantly associated with leaf rust resistance in a diverse panel of 119 wheat varieties mainly from China. Four candidate genes encoding a lectin-receptor kinase protein, F-box family protein, ankyrin repeat domain protein, and putative ABC transporter, respectively, were identified in genetic regions of the four QTL. These findings provide valuable QTL and breeding available KASP markers, facilitating the improvement of leaf rust resistance in wheat through marker-assisted breeding.
546			_aText in English
597			_dNational Natural Science Foundation of China _dNational Key Research and Development Program _dChinese Academy of Agricultural Sciences (CAAS) _dChina Association for Science and Technology (CAST) _dNanfan Special Project
650		7	_aTriticum aestivum _2AGROVOC _91296
650		7	_aDisease resistance _2AGROVOC _91077
650		7	_aQuantitative Trait Loci _2AGROVOC _91853
700	0		_aLei Li _917301
700	0		_aZaifeng Li _93343
700	0		_aYubing Tian _91856
700	0		_aFangping Yang _937671
700	0		_aShuanghe Cao _95093
700	0		_aXianchun Xia _9377
700	0		_aYongjing Ni _936835
700	1		_aHe Zhonghu _gGlobal Wheat Program _8INT2411 _9838
700	0		_aYan Zhang _916460
700	0		_aYong Zhang _91857
700	0		_aJindong Liu _93032
773	0		_tPhytopathology Research _gv. 7, no. 1, art. 57 _dUnited Kingdom : BioMed Central Ltd., 2025. _x2096-5362
856	4		_yOpen Access through DSpace _uhttps://hdl.handle.net/10883/35809
942			_cJA _n0 _2ddc
999			_c69065 _d69057