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022 _a0011-183X
022 _a1435-0653 (Online)
024 8 _ahttps://doi.org/10.1002/csc2.21203
040 _aMX-TxCIM
041 _aeng
100 1 _aWanjala, B.W.
_939329
245 1 0 _aLoop-mediated isothermal amplification assay :
_ba novel disease diagnostics tool in sweetpotato seed quality assurance
260 _aUnited States of America :
_bJohn Wiley & Sons,
_c2024.
500 _aPeer review
520 _aSweetpotato is an important food crop in global production. However, sweetoptato viruses pose a threat to sustainable agriculture and cause significant economic loss. More than 30 viruses have been reported to date, with sweet potato feathery mottle virus (SPFMV) and sweet potato chlorotic stunt virus (SPCSV) occurring frequently and in combination, causing sweetpotato virus disease. The detection of viruses directly from sweetpotato is still a challenge, and efforts are being made toward this front. Therefore, rapid detection of viruses is critical for effective control. Current diagnostic tests are not sufficiently sensitive to reliably detect viruses directly from sweetpotato and require expensive laboratory equipment and a high level of skilled experience. Loop-mediated isothermal amplification (LAMP) is sensitive and specific for both DNA/RNA amplification; it is affordable and its characteristics make it potentially suitable for on-site testing. LAMP assays have been developed for several sweetpotato viruses: SPCSV, SPFMV, and sweet potato leaf curl virus (and related sweepoviruses). Laboratory validation showed a 100% diagnostic sensitivity for all three viruses. The LAMP on-site testing results were comparable to those of polymerase chain reaction and reverse transcriptase polymerase chain reaction confirmatory laboratory tests. Interlab validation and packaging into affordable kits will ensure high adoption in sub-Saharan Africa. The LAMP assay can be used for field surveys and monitoring the phytosanitary status of pre-basic seed production in quarantine or certification program. This guarantees pathogen-free planting material enters the seed system. We discuss opportunities for LAMP as a diagnostic assay for the rapid detection of sweetpotato viruses and its adoption as a quality control system for planting materials.
546 _aText in English
650 7 _aSweet potatoes
_2AGROVOC
_92711
650 7 _aFood crops
_2AGROVOC
_91994
650 7 _aSustainable agriculture
_2AGROVOC
_92327
650 7 _aEconomic losses
_2AGROVOC
_917225
650 7 _aViroses
_2AGROVOC
_94323
650 7 _aSeed production
_2AGROVOC
_91253
700 1 _aKreuze, J.F.
_918973
700 1 _aMcEwan, M.A.
_918467
700 1 _aLow, J.W.
_939305
773 0 _dUnited States of America : John Wiley & Sons, 2024.
_gv. 64, no. 3, p. 1183-1192
_tCrop Science
_wG444244
_x0011-183X
942 _2ddc
_cJA
_n0
999 _c68954
_d68946