000			03100nab|a22003977a|4500
001			68936
003			MX-TxCIM
005			20251217111431.0
008			20255s2025|||||sz|||p|op||||00||0|eng|dd
022			_a2076-0817 (Online)
024	8		_ahttps://doi.org/10.3390/pathogens14050490
040			_aMX-TxCIM
041			_aeng
100	1		_aMandal, R. _936179
245	1	0	_aEvaluation of fusarium head blight resistance through a genome-wide association study in CIMMYT and South Asian wheat germplasm
260			_aSwitzerland : _bMDPI, _c2025.
500			_aPeer review
500			_aOpen Access
520			_aFusarium head blight (FHB) is an important disease throughout the world due to its strong association with yield reduction, quality deterioration, and mycotoxin contamination in wheat. The use of FHB-resistant genotypes in wheat production can significantly reduce damage. The current study screened a panel of bread wheat from CIMMYT and South Asian countries for FHB resistance to identify promising genotypes useful for wheat breeding and to map the associated genomic regions and linked molecular markers through a genome-wide association study (GWAS). Spray-inoculated field experiments were conducted at CIMMYT, Mexico, over three years, and a wide range of phenotypic variations was observed. Four lines, CIM-39, CIM-29, CIM-9, and CIM-3, exhibited consistent resistance across experiments, with FHB indices ranging from 6.5 to 8.1. Genotyping was conducted using the Illumina Infinium 15 K Bead Chip, and 11,184 high-quality SNP markers were obtained and used for GWAS. Nineteen significant marker-trait associations (MTAs) were detected, among which MTAs at Ra_c58315_265 on 1A and Tdurum_contig102328_129 and Ku_c20136_198 on 7B showed reproducible results, with phenotypic effects on FHB resistance of 6.05%, 3.54%, and 3.92%, respectively. Several genes associated with disease resistance were found near the significant SNPs. The identified resistant genotypes and markers may be useful in future marker-assisted breeding in wheat.
546			_aText in English
597			_bAccelerated Breeding _bPlant Health _dIndian Council of Agricultural Research (ICAR) _dUnited States Agency for International Development (USAID) _dCGIAR Trust Fund _uhttps://hdl.handle.net/10568/175606 _fBreeding for Tomorrow
650		7	_aFusarium _2AGROVOC _92705
650		7	_aGenome-wide association studies _2AGROVOC _931443
650		7	_aWheat _2AGROVOC _91310
650		7	_aSingle nucleotide polymorphisms _2AGROVOC _910805
651		7	_aSouth Asia _2AGROVOC _91956
700	1		_aXinyao He _gGlobal Wheat Program _8INT3297 _9913
700	1		_aSingh, G.P. _918282
700	1		_aKabir, M.R. _915565
700	1		_aJoshi, A.K. _gGlobal Wheat Program _gFormerly Borlaug Institute for South Asia _8INT2917 _9873
700	1		_aPawan Kumar Singh _gGlobal Wheat Program _8INT2868 _9868
773	0		_tPathogens _gv. 14, no. 5, art. 490 _dSwitzerland : MDPI, 2025. _x2076-0817
856	4		_yOpen Access through DSpace _uhttps://hdl.handle.net/10883/35755
942			_cJA _n0 _2ddc
999			_c68936 _d68928