| 000 | 04866nab|a22009497a|4500 | ||
|---|---|---|---|
| 001 | 68800 | ||
| 003 | MX-TxCIM | ||
| 005 | 20250605093354.0 | ||
| 008 | 20255s2025|||||-us||p|op||||00||0|eng|dd | ||
| 022 | _a1544-9173 | ||
| 022 | _a1545-7885 (Online) | ||
| 024 | 8 | _ahttps://doi.org/10.1371/journal.pbio.3003097 | |
| 040 | _aMX-TxCIM | ||
| 041 | _aeng | ||
| 100 | 0 |
_aJigisha Jigisha _939014 |
|
| 245 | 1 | 0 | _aPopulation genomics and molecular epidemiology of wheat powdery mildew in Europe |
| 260 |
_aUnited States of America : _bPublic Library of Science, _c2025. |
||
| 500 | _aPeer review | ||
| 500 | _aOpen Access | ||
| 520 | _aAgricultural diseases are a major threat to sustainable food production. Yet, for many pathogens we know exceptionally little about their epidemiological and population dynamics, and this knowledge gap is slowing the development of efficient control strategies. Here we study the population genomics and molecular epidemiology of wheat powdery mildew, a disease caused by the biotrophic fungus Blumeria graminis forma specialis tritici (Bgt). We sampled Bgt across two consecutive years, 2022 and 2023, and compiled a genomic dataset of 415 Bgt isolates from 22 countries in Europe and surrounding regions. We identified a single epidemic unit in the north of Europe, consisting of a highly homogeneous population. Conversely, the south of Europe hosts smaller local populations which are less interconnected. In addition, we show that the population structure can be largely predicted by the prevalent wind patterns. We identified several loci that were under selection in the recent past, including fungicide targets and avirulence genes. Some of these loci are common between populations, while others are not, suggesting different local selective pressures. We reconstructed the evolutionary history of one of these loci, AvrPm17, coding for an effector recognized by the wheat receptor Pm17. We found evidence for a soft sweep on standing genetic variation. Multiple AvrPm17 haplotypes, which can partially escape recognition by Pm17, spread rapidly throughout the continent upon its introduction in the early 2000s. We also identified a new virulent variant, which emerged more recently and can evade Pm17 resistance altogether. Overall, we highlight the potential of genomic surveillance in resolving the evolutionary and epidemiological dynamics of agricultural pathogens, as well as in guiding control strategies. | ||
| 546 | _aText in English | ||
| 591 | _aAkin, B. : Not in IRS staff list but CIMMYT Affiliation | ||
| 597 | _dSwiss National Science Foundation (SNSF) | ||
| 650 | 7 |
_aGenomics _2AGROVOC _91132 |
|
| 650 | 7 |
_aEpidemiology _2AGROVOC _96627 |
|
| 650 | 7 |
_aWheat _2AGROVOC _91310 |
|
| 650 | 7 |
_aPowdery mildews _2AGROVOC _95953 |
|
| 650 | 7 |
_aDiseases _2AGROVOC _95952 |
|
| 651 | 7 |
_aEurope _2AGROVOC _94645 |
|
| 700 | 1 |
_aLy, J. _939016 |
|
| 700 | 1 |
_aMinadakis, N. _939017 |
|
| 700 | 1 |
_aFreund, F. _939018 |
|
| 700 | 1 |
_aKunz, L. _939019 |
|
| 700 | 1 |
_aPiechota,U. _939021 |
|
| 700 | 1 |
_aAkin, B. _91340 |
|
| 700 | 1 |
_aBalmas, V. _939022 |
|
| 700 |
_aBen-David, R. _910188 |
||
| 700 | 1 |
_aBencze, S. _925554 |
|
| 700 | 1 |
_aBourras, S. _938083 |
|
| 700 | 1 |
_aBozzoli, M. _938080 |
|
| 700 | 1 |
_aCotuna, O. _939023 |
|
| 700 | 1 |
_aCouleaud, G. _939024 |
|
| 700 | 1 |
_aCséplő, M. _939026 |
|
| 700 | 1 |
_aCzembor, P. _939027 |
|
| 700 | 1 |
_aDesiderio, F. _93081 |
|
| 700 | 1 |
_aDörnte, J. _939028 |
|
| 700 | 1 |
_aDreiseitl, A. _939031 |
|
| 700 | 1 |
_aFeechan, A. _939033 |
|
| 700 | 1 |
_aGadaleta, A. _920662 |
|
| 700 | 1 |
_aGauthier, K. _939034 |
|
| 700 | 1 |
_aGiancaspro, A. _939035 |
|
| 700 | 1 |
_aGiove, S.L. _939036 |
|
| 700 | 1 |
_aHandley-Cornillet, A. _939037 |
|
| 700 | 1 |
_aHubbard, A. _96069 |
|
| 700 | 1 |
_aKaraoglanidis. G. _939038 |
|
| 700 | 1 |
_aKildea, S. _939039 |
|
| 700 | 1 |
_aKoc, E. _94954 |
|
| 700 | 1 |
_aLiatukas, Z. _939040 |
|
| 700 | 1 |
_ada Silva Sabino Lopes, M. _917804 |
|
| 700 | 1 |
_aMascher, F. _925232 |
|
| 700 | 1 |
_aMcCabe, C. _939041 |
|
| 700 | 1 |
_aMiedaner, T. _91517 |
|
| 700 | 1 |
_aMartínez-Moreno, F. _927385 |
|
| 700 | 1 |
_aNellist, C.F. _934407 |
|
| 700 | 1 |
_aOkoń, S. _939042 |
|
| 700 | 1 |
_aPraz, C. _939043 |
|
| 700 | 1 |
_aSánchez-Martín, J. _924702 |
|
| 700 | 1 |
_aSărăţeanu, V. _939045 |
|
| 700 | 1 |
_aSchulz, P. _934410 |
|
| 700 | 1 |
_aSchwartz, N. _939046 |
|
| 700 | 1 |
_aSeghetta, D. _939047 |
|
| 700 | 1 |
_aSolís Martel, I. _939048 |
|
| 700 | 1 |
_aŠvarta, A. _939049 |
|
| 700 | 1 |
_aTestempasis. S. _939050 |
|
| 700 | 1 |
_aVillegas, D. _92359 |
|
| 700 | 1 |
_aWidrig, V. _924907 |
|
| 700 | 1 |
_aMenardo, F. _939052 |
|
| 773 | 0 |
_tPLoS Biology _gv. 23, no. 5, e3003097 _dUnited States of America : Public Library of Science, 2025. _x1544-9173 _wu79395 |
|
| 856 | 4 |
_yOpen Access through DSpace _uhttps://hdl.handle.net/10883/35693 |
|
| 942 |
_cJA _n0 _2ddc |
||
| 999 |
_c68800 _d68792 |
||