| 000 | 02901nab|a22005057a|4500 | ||
|---|---|---|---|
| 001 | 68789 | ||
| 003 | MX-TxCIM | ||
| 005 | 20250516155500.0 | ||
| 008 | 20254s2025|||||-uk||p|op||||00||0|eng|dd | ||
| 022 | _a1087-0156 | ||
| 022 | _a1546-1696 (Online) | ||
| 024 | 8 | _ahttps://doi.org/10.1038/s41587-025-02611-1 | |
| 040 | _aMX-TxCIM | ||
| 041 | _aeng | ||
| 100 | 1 |
_aGriffiths, C.A. _917212 |
|
| 245 | 1 | 0 | _aMembrane-permeable trehalose 6-phosphate precursor spray increases wheat yields in field trials |
| 260 |
_aUnited Kingdom : _bNature Research, _c2025. |
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| 500 | _aPeer review | ||
| 500 | _aOpen Access | ||
| 520 | _aTrehalose 6-phosphate (T6P) is an endogenous sugar signal in plants that promotes growth, yet it cannot be introduced directly into crops or fully genetically controlled. Here we show that wheat yields were improved using a timed microdose of a plant-permeable, sunlight-activated T6P signaling precursor, DMNB-T6P, under a variety of agricultural conditions. Under both well-watered and water-stressed conditions over 4 years, DMNB-T6P stimulated yield of three elite varieties. Yield increases were an order of magnitude larger than average annual genetic gains of breeding programs and occurred without additional water or fertilizer. Mechanistic analyses reveal that these benefits arise from increased CO2 fixation and linear electron flow ('source') as well as from increased starchy endosperm volume, enhanced grain sieve tube development and upregulation of genes for starch, amino acid and protein synthesis ('sink'). These data demonstrate a step-change, scalable technology with net benefit to the environment that could provide sustainable yield improvements of diverse staple cereal crops. | ||
| 546 | _aText in English | ||
| 597 |
_dBiotechnology and Biological Sciences Research Council (BBSRC) _dEngineering and Physical Sciences Research Council (EPSRC) |
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| 650 | 7 |
_aTrehalose _2AGROVOC _918783 |
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| 650 | 7 |
_aPhosphates _2AGROVOC _95224 |
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| 650 | 7 |
_aWheat _2AGROVOC _91310 |
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| 650 | 7 |
_aYields _2AGROVOC _91313 |
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| 650 | 7 |
_aField Experimentation _2AGROVOC _98629 |
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| 700 | 0 |
_aXiaochao Xue _938795 |
|
| 700 | 1 |
_aMiret, J.A. _938796 |
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| 700 | 1 |
_aSalvagiotti, F. _938797 |
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| 700 | 1 |
_8001712527 _aAcevedo-Siaca L.G. _gGlobal Wheat Program _919854 |
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| 700 | 1 |
_aGimeno, J. _8I1706704 _gGlobal Wheat Program _94777 |
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| 700 | 1 |
_aReynolds, M.P. _gGlobal Wheat Program _8INT1511 _9831 |
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| 700 | 1 |
_aHassall, K.L. _919432 |
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| 700 | 1 |
_aHalsey, K. _938798 |
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| 700 | 1 |
_aPuranik, S. _918074 |
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| 700 | 1 |
_aOszvald, M. _938799 |
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| 700 | 1 |
_aKurup, S. _938800 |
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| 700 | 1 |
_aDavis, B.G. _938801 |
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| 700 | 1 |
_aPaul, M.J. _917213 |
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| 773 | 0 |
_tNature Biotechnology _dUnited Kingdom : Nature Research, 2025. _x1087-0156 _gIn press |
|
| 856 | 4 |
_yOpen Access through DSpace _uhttps://hdl.handle.net/10883/35641 |
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| 942 |
_cJA _n0 _2ddc |
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| 999 |
_c68789 _d68781 |
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