000			03677nab|a22005417a|4500
001			67604
003			MX-TxCIM
005			20241126142700.0
008			20243s2024||||mx |||p|op||||00||0|eng|d
022			_a0040-5752
022			_a1432-2242 (Online)
024	8		_ahttps://doi.org/10.1007/s00122-024-04661-6
040			_aMX-TxCIM
041			_aeng
100	0		_aMengjing Sun _919597
245	1	0	_aMolecular characterization of QTL for grain zinc and iron concentrations in wheat landrace Chinese Spring
260			_bSpringer, _c2024. _aBerlin (Germany) :
500			_aPeer review
520			_aWheat is a major source of dietary energy for the growing world population. Developing cultivars with enriched zinc and iron can potentially alleviate human micronutrient deficiency. In this study, a recombinant inbred line (RIL) population with 245 lines derived from cross Zhou 8425B/Chinese Spring was used to detect quantitative trait loci (QTL) for grain zinc concentration (GZnC) and grain iron concentration (GFeC) across four environments. Three stable QTL for GZnC with all favorable alleles from Chinese Spring were identified on chromosomes 3BL, 5AL, and 5BL. These QTL explaining maxima of 8.7%, 5.8%, and 7.1% of phenotypic variances were validated in 125 resequenced wheat accessions encompassing both landraces and modern cultivars using six kompetitive allele specific PCR (KASP) assays. The frequencies of favorable alleles for QGZnCzc.caas-3BL, QGZnCzc.caas-5AL and QGZnCzc.caas-5BL were higher in landraces (90.4%, 68.0%, and 100.0%, respectively) compared to modern cultivars (45.9%, 35.4%, and 40.9%), suggesting they were not selected in breeding programs. Candidate gene association studies on GZnC in the cultivar panel further delimited the QTL into 8.5 Mb, 4.1 Mb, and 47.8 Mb regions containing 46, 4, and 199 candidate genes, respectively. The 5BL QTL located in a region where recombination was suppressed. Two stable and three less stable QTL for GFeC with favorable alleles also from Chinese Spring were identified on chromosomes 4BS (Rht-B1a), 4DS (Rht-D1a), 1DS, 3AS, and 6DS. This study sheds light on the genetic basis of GZnC and GFeC in Chinese Spring and provides useful molecular markers for wheat biofortification.
546			_aText in English
591			_aYuanfeng Hao : No CIMMYT Affiliation
650		7	_aMolecular characterization _2AGROVOC _929016
650		7	_aQuantitative Trait Loci _2AGROVOC _91853
650		7	_aWheat _2AGROVOC _91310
650		7	_aZinc _2AGROVOC _91315
650		7	_aIron _2AGROVOC _93544
650		7	_aField Experimentation _2AGROVOC _98629
651		7	_aChina _2AGROVOC _93990
700	0		_aJingyang Tong _919596
700	0		_aYan Dong _95886
700	0		_aZongjun Pu _919742
700	0		_aJianmin Zheng _926840
700	0		_aYelun Zhang _91855
700	0		_aXueyong Zhang _929307
700	0		_aChenyang Hao _925310
700	0		_aXiaowan Xu _926394
700	0		_aQiang Cao _916526
700	1		_aAwais Rasheed _gGlobal Wheat Program _8I1706474 _91938
700	0		_aMohamed Badry Ali _934247
700	0		_aShuanghe Cao _95093
700	0		_aXianchun Xia _9377
700	1		_aHe Zhonghu _gGlobal Wheat Program _8INT2411 _9838
700	0		_aZhongfu Ni _928381
700	1		_aYuanfeng Hao _gGlobal Wheat Program _8INT3329 _9919
773	0		_tTheoretical and Applied Genetics _dBerlin (Germany) : Springer, 2024. _x0040-5752 _gv. 137, art. 148 _wG444762
942			_cJA _n0 _2ddc
999			_c67604 _d67596