000			03227nab|a22004097a|4500
001			67422
003			MX-TxCIM
005			20240430234232.0
008			20244s2024||||mx |||p|op||||00||0|eng|d
022			_a0040-5752
022			_a1432-2242 (Online)
024	8		_ahttps://doi.org/10.1007/s00122-021-03859-2
040			_aMX-TxCIM
041			_aeng
100	1		_aDelfni, J. _933682
245	1	0	_aGenome-wide association study for grain mineral content in a Brazilian common bean diversity panel
260			_bSpringer Verlag, _c2021. _aBerlin (Germany) :
500			_aPeer review
520			_aBiofortification is one of the strategies developed to address malnutrition in developing countries, the aim of which is to improve the nutritional content of crops. The common bean (Phaseolus vulgaris L.), a staple food in several African and Latin American countries, has excellent nutritional attributes and is considered a strong candidate for biofortification. The objective of this study was to identify genomic regions associated with nutritional content in common bean grains using 178 Mesoamerican accessions belonging to a Brazilian Diversity Panel (BDP) and 25,011 good-quality single nucleotide polymorphisms. The BDP was phenotyped in three environments for nine nutrients (phosphorus, potassium, calcium, magnesium, copper, manganese, sulfur, zinc, and iron) using four genome-wide association multi-locus methods. To obtain more accurate results, only quantitative trait nucleotides (QTNs) that showed repeatability (i.e., those detected at least twice using different methods or environments) were considered. Forty-eight QTNs detected for the nine minerals showed repeatability and were considered reliable. Pleiotropic QTNs and overlapping genomic regions surrounding the QTNs were identified, demonstrating the possible association between the deposition mechanisms of different nutrients in grains. The accumulation of favorable alleles in the same accession was associated with a gradually increasing nutrient content in the grain. The BDP proved to be a valuable source for association studies. The investigation of different methods and environments showed the reliability of markers associated with minerals. The loci identified in this study will potentially contribute to the improvement of Mesoamerican common beans, particularly carioca and black beans, the main groups consumed in Brazil.
546			_aText in English
650		7	_2AGROVOC _931443 _aGenome-wide association studies
650		7	_2AGROVOC _91138 _aGrain
650		7	_2AGROVOC _927973 _aCommon beans
650		7	_2AGROVOC _91135 _aGenotyping-by-sequencing
650		7	_2AGROVOC _91193 _aNutritive value
651		7	_2AGROVOC _95489 _aBrazil
700	1		_933683 _aModa‑Cirino, V.
700	1		_933684 _ados Santos Neto, J.
700	0		_933685 _aDouglas Mariani Zefa
700	1		_933686 _aFernando Nogueira, A.
700	1		_933687 _aBrandão Ribeiro, L.A.
700	1		_922219 _aRuas, P.M.
700	1		_99157 _aGepts, P.
700	1		_933688 _aAzeredo Gonçalves. L.S.
773	0		_tTheoretical and Applied Genetics _dBerlin (Germany) : Springer Verlag, 2021. _gv. 134, p. 2795–2811 _x0040-5752 _wG444762
942			_cJA _n0 _2ddc
999			_c67422 _d67414