000			03437nab|a22005297a|4500
001			66505
003			MX-TxCIM
005			20231010190848.0
008			20239s2023||||mx |||p|op||||00||0|eng|d
022			_a0040-5752
022			_a1432-2242 (Online)
024	8		_ahttps://doi.org/10.1007/s00122-023-04467-y
040			_aMX-TxCIM
041			_aeng
100	0		_919597 _aMengjing Sun
245	1	0	_aMolecular characterization of stable QTL and putative candidate genes for grain zinc and iron concentrations in two related wheat populations
260			_bSpringer Verlag, _c2023. _aBerlin (Germany) :
500			_aPeer review
520			_aMicronutrient malnutrition is one of the most common public health problems in the world. Biofortification, the most attractive and sustainable solution to surmount malnutrition requires the development of micronutrient enriched new crop cultivars. In this study, two recombinant inbred line (RIL) populations, ZM175/XY60 and ZM175/LX987, were used to identify QTL for grain zinc concentration (GZnC), grain iron concentration (GFeC) and thousand grain weight (TGW). Eight QTL for GZnC, six QTL for GFeC and five QTL for TGW were detected. Three QTL on chromosomes 2DL and 4BS and chromosome 6A showed pleiotropic effects on all three traits. The 4BS and 6A QTL also increased plant height and might be Rht-B1a and Rht25a, respectively. The 2DL locus within a suppressed recombination region was identified in both RIL populations and the favorable allele simultaneously increasing GZnC, GFeC and TGW was contributed by XY60 and LX987. A QTL on chromosome 6DL associated only with GZnC was detected in ZM175/XY60 and was validated in JD8/AK58 RILs using kompetitive allele-specific PCR (KASP) marker K_AX-110119937. Both the 2DL and 6DL QTL were new loci for GZnC. Based on gene annotations, sequence variations and expression profiles, the phytic acid biosynthesis gene TaIPK1-2D and nicotianamine synthase gene TaNAS10-6D were predicted as candidate genes. Their gene-based KASP markers were developed and validated in a cultivar panel of 343 wheat accessions. This study investigated the genetic basis of GZnC and GFeC and provided valuable candidate genes and markers for breeding Zn- and Fe-enriched wheat.
546			_aText in English
591			_aYuanfeng Hao : No CIMMYT Affiliation
650		7	_aMolecular characterization _929016 _2AGROVOC
650		7	_aQuantitative Trait Loci _91853 _2AGROVOC
650		7	_aGrain _91138 _2AGROVOC
650		7	_aZinc _91315 _2AGROVOC
650		7	_aIron _93544 _2AGROVOC
650		7	_aWheat _91310 _2AGROVOC
650		7	_aChromosomes _97014 _2AGROVOC
700	0		_931815 _aQiaoling Luo
700	0		_931816 _aQi Zheng
700	0		_919596 _aJingyang Tong
700	0		_910965 _aYue Wang
700	0		_919337 _aJie Song
700	0		_91855 _aYelun Zhang
700	0		_919742 _aZongjun Pu
700	0		_926840 _aJianmin Zheng
700	0		_926841 _aLianzheng Liu
700	0		_931817 _aAnding Zhou
700	1		_91938 _aRasheed, A. _8I1706474 _gGlobal Wheat Program
700	0		_914174 _aMing Li
700	0		_95093 _aShuanghe Cao
700	0		_9377 _aXianchun Xia
700	1		_9838 _aHe Zhonghu _8INT2411 _gGlobal Wheat Program
700	1		_9919 _aYuanfeng Hao _8INT3329 _gGlobal Wheat Program
773	0		_tTheoretical and Applied Genetics _gv. 136, art. 217 _dBerlin (Germany) : Springer Verlag, 2023. _x0040-5752 _wG444762
942			_cJA _n0 _2ddc
999			_c66505 _d66497