000			03529nab|a22003977a|4500
001			66425
003			MX-TxCIM
005			20231101181226.0
008			20238s2023||||mx |||p|op||||00||0|eng|d
022			_a2045-2322 (Online)
024	8		_ahttps://doi.org/10.1038/s41598-023-39720-3
040			_aMX-TxCIM
041			_aeng
100	1		_aPetroli, C.D. _8CPEC01 _91408 _gGenetic Resources Program
245	1	0	_aGenetic variation among elite inbred lines suggests potential to breed for BNI-capacity in maize
260			_bNature Publishing Group, _c2023. _aLondon (United Kingdom) :
500			_aPeer review
500			_aOpen Access
520			_aBiological nitrification inhibition (BNI) is a plant function where root systems release antibiotic compounds (BNIs) specifically aimed at suppressing nitrifiers to limit soil-nitrate formation in the root zone. Little is known about BNI-activity in maize (Zea mays L.), the most important food, feed, and energy crop. Two categories of BNIs are released from maize roots; hydrophobic and hydrophilic BNIs, that determine BNI-capacity in root systems. Zeanone is a recently discovered hydrophobic compound with BNI-activity, released from maize roots. The objectives of this study were to understand/quantify the relationship between zeanone activity and hydrophobic BNI-capacity. We assessed genetic variability among 250 CIMMYT maize lines (CMLs) characterized for hydrophobic BNI-capacity and zeanone activity, towards developing genetic markers linked to this trait in maize. CMLs with high BNI-capacity and ability to release zeanone from roots were identified. GWAS was performed using 27,085 SNPs (with unique positions on the B73v.4 reference genome, and false discovery rate = 10), and phenotypic information for BNI-capacity and zeanone production from root systems. Eighteen significant markers were identified; three associated with specific BNI-activity (SBNI), four with BNI-activity per plant (BNIPP), another ten were common between SBNI and BNIPP, and one with zeanone release. Further, 30 annotated genes were associated with the significant SNPs; most of these genes are involved in pathways of "biological process", and one (AMT5) in ammonium regulation in maize roots. Although the inbred lines in this study were not developed for BNI-traits, the identification of markers associated with BNI-capacity suggests the possibility of using these genomic tools in marker-assisted selection to improve hydrophobic BNI-capacity in maize.
546			_aText in English
591			_aFranco, J. : No CIMMYT Affiliation
650		7	_2AGROVOC _91129 _aGenetic variation
650		7	_2AGROVOC _91155 _aInbred lines
650		7	_2AGROVOC _91173 _aMaize
650		7	_2AGROVOC _910737 _aMarker-assisted selection
700	0		_aGuntur Venkata Subbarao _92828
700	1		_aBurgueño, J. _8INT3239 _9907 _gGenetic Resources Program
700	0		_aTadashi Yoshihashi _92829
700	1		_aHuihui Li _8CLIH01 _9764 _gGenetic Resources Program
700	1		_aFranco, J. _8CFRN01 _9494 _gFormerly Genetic Resources Program
700	1		_aPixley, K.V. _8INT1617 _9832 _gGenetic Resources Program
773	0		_tScientific Reports _gv. 13, p. 13422 _dLondon (United Kingdom) : Nature Publishing Group, 2023 _wa58025 _x2045-2322
856	4		_yOpen Access through DSpace _uhttps://hdl.handle.net/10883/22693
942			_cJA _n0 _2ddc
999			_c66425 _d66417