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022			_a0016-6731
022			_a1943-2631 (Online)
024	8		_2https://doi.org/10.1093/genetics/iyad059
040			_aMX-TxCIM
041	0		_aeng
100	1		_aLegarra, A. _96003
245	1	0	_aImpact of interpopulation distance on dominance variance and average heterosis in hybrid populations within species
260			_c2023. _aUnited Kingdom : _bOxford University Press,
500			_aPeer review
500			_aReference only
520			_aInterpopulation improvement for crosses of close populations in crops and livestock depends on the amount of heterosis and the amount of variance of dominance deviations in the hybrids. It has been intuited that the further the distance between populations, the lower the amount of dominance variation and the higher the heterosis. Although experience in speciation and interspecific crosses shows, however, that this is not the case when populations are so distant – here we confine ourselves to the case of not-too-distant populations typical in crops and livestock. We present equations that relate the distance between two populations, expressed as Nei’s genetic distance or as correlation of allele frequencies, quadratically to the amount of dominance deviations across all possible crosses and linearly to the expected heterosis averaging all possible crosses. The amount of variation of dominance deviations decreases with genetic distance until the point where allele frequencies are uncorrelated, and then increases for negatively correlated frequencies. Heterosis always increases with Nei’s genetic distance. These expressions match well and complete previous theoretical and empirical findings. In practice, and for close enough populations, they mean that unless frequencies are negatively correlated, selection for hybrids will be more efficient when populations are distant.
546			_aText in English
650		7	_926603 _aCross-breeding _2AGROVOC
650		7	_94749 _aSelection _2AGROVOC
650		7	_92526 _aGenetic distance _2AGROVOC
700	1		_926628 _aGonzález-Diéguez, D.O. _81707522 _gGlobal Wheat Program
700	1		_94628 _aCharcosset, A.
700	1		_926629 _aVitezica, Z.G.
773	0		_tGenetics _gv. 224, no. 2, art. iyad059 _dUnited Kingdom : Oxford University Press, 2023. _x1943-2631 _wG444332
942			_cJA _2ddc _n0
999			_c66246 _d66238