000			03944nab|a22004457a|4500
001			65833
003			MX-TxCIM
005			20240919021005.0
008			20225s2022||||mx |||p|op||||00||0|eng|d
022			_a1664-462X
024	8		_ahttps://doi.org/10.3389/fpls.2022.880138
040			_aMX-TxCIM
041			_aeng
100	0		_aDemei Liu _917337
245	1	0	_aStripe rust and leaf rust resistance in CIMMYT wheat line “Mucuy” is conferred by combinations of race-specific and adult-plant resistance loci
260			_bFrontiers,, _c2022. _aSwitzerland :
500			_aPeer review
500			_aOpen Access
520			_aDeveloping wheat varieties with durable resistance is a core objective of the International Maize and Wheat Improvement Center (CIMMYT) and many other breeding programs worldwide. The CIMMYT advanced wheat line “Mucuy” displayed high levels of resistance to stripe rust (YR) and leaf rust (LR) in field evaluations in Mexico and several other countries. To determine the genetic basis of YR and LR resistance, 138 F5 recombinant inbred lines (RILs) derived from the cross of Apav#1× Mucuy were phenotyped for YR responses from 2015 to 2020 at field sites in India, Kenya, and Mexico, and LR in Mexico. Seedling phenotyping for YR and LR responses was conducted in the greenhouse in Mexico using the same predominant races as in field trials. Using 12,681 polymorphic molecular markers from the DArT, SNP, and SSR genotyping platforms, we constructed genetic linkage maps and QTL analyses that detected seven YR and four LR resistance loci. Among these, a co-located YR/LR resistance loci was identified as Yr29/Lr46, and a seedling stripe rust resistance gene YrMu was mapped on the 2AS/2NS translocation. This fragment also conferred moderate adult plant resistance (APR) under all Mexican field environments and in one season in Kenya. Field trial phenotyping with Lr37-virulent Puccinia triticina races indicated the presence of an APR QTL accounting for 18.3–25.5% of the LR severity variation, in addition to a novel YR resistance QTL, QYr.cim-3DS, derived from Mucuy. We developed breeder-friendly KASP and indel molecular markers respectively for Yr29/Lr46 and YrMu. The current study validated the presence of known genes and identified new resistance loci, a QTL combination effect, and flanking markers to facilitate accelerated breeding for genetically complex, durable rust resistance.
546			_aText in English
591			_aCaixia Lan : No CIMMYT Affiliation
610	2	7	_9978 _aCentro Internacional de Mejoramiento de Maiz y Trigo (CIMMYT)
650		7	_aRusts _2AGROVOC _91251
650		7	_aPuccinia striiformis _2AGROVOC _91842
650		7	_aQuantitative Trait Loci _2AGROVOC _91853
650		7	_aAdult plant resistance _2AGROVOC _922056
650		7	_aWheat _2AGROVOC _91310
700	0		_aChan Yuan _917336
700	1		_aSingh, R.P. _9825 _8INT0610 _gGlobal Wheat Program
700	1		_aRandhawa, M.S. _91665 _8I1706569 _gGlobal Wheat Program
700	1		_aBhavani, S. _9867 _8INT2843 _gGlobal Wheat Program
700	1		_aKumar, U. _gFormerly Borlaug Institute for South Asia (BISA) _8INT3331 _9921
700	1		_aHuerta-Espino, J. _gGlobal Wheat Program _8CHUE01 _9397
700	1		_aLagudah, E.S. _91697
700	1		_aCaixia Lan _9901 _8INT3206 _gGlobal Wheat Program
773	0		_tFrontiers in Plant Science _gv. 13, art. 880138 _dSwitzerland : Frontiers, 2022. _x1664-462X _w56875
856	4		_yOpen Access through DSpace _uhttps://hdl.handle.net/10883/22369
942			_cJA _n0 _2ddc
999			_c65833 _d65825