| 000 | 03537nab|a22006857a|4500 | ||
|---|---|---|---|
| 001 | 65453 | ||
| 003 | MX-TxCIM | ||
| 005 | 20240919021233.0 | ||
| 008 | 202212s2022||||mx |||p|op||||00||0|eng|d | ||
| 022 | _a2041-1723 (Online) | ||
| 024 | 8 | _ahttps://doi.org/10.1038/s41467-022-30784-9 | |
| 040 | _aMX-TxCIM | ||
| 041 | _aeng | ||
| 100 | 1 |
_aLin, G. _928197 |
|
| 245 | 1 | 0 | _aCloning of the broadly effective wheat leaf rust resistance gene Lr42 transferred from Aegilops tauschii |
| 260 |
_bNature Publishing Group, _c2022. _aUnited Kingdom : |
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| 500 | _aPeer review | ||
| 500 | _aOpen Access | ||
| 520 | _aThe wheat wild relative Aegilops tauschii was previously used to transfer the Lr42 leaf rust resistance gene into bread wheat. Lr42 confers resistance at both seedling and adult stages, and it is broadly effective against all leaf rust races tested to date. Lr42 has been used extensively in the CIMMYT international wheat breeding program with resulting cultivars deployed in several countries. Here, using a bulked segregant RNA-Seq (BSR-Seq) mapping strategy, we identify three candidate genes for Lr42. Overexpression of a nucleotide-binding site leucine-rich repeat (NLR) gene AET1Gv20040300 induces strong resistance to leaf rust in wheat and a mutation of the gene disrupted the resistance. The Lr42 resistance allele is rare in Ae. tauschii and likely arose from ectopic recombination. Cloning of Lr42 provides diagnostic markers and over 1000 CIMMYT wheat lines carrying Lr42 have been developed documenting its widespread use and impact in crop improvement. | ||
| 546 | _aText in English | ||
| 650 | 7 |
_aAlleles _2AGROVOC _92185 |
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| 650 | 7 |
_aClones _2AGROVOC _98955 |
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| 650 | 7 |
_aGene Expression _2AGROVOC _98835 |
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| 650 | 7 |
_aGrasses _2AGROVOC _98943 |
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| 650 | 7 |
_aMutation _2AGROVOC _93635 |
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| 650 | 7 |
_aRusts _2AGROVOC _91251 |
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| 650 | 7 |
_aWheat _2AGROVOC _91310 |
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| 650 | 7 |
_aBasidiomycota _2AGROVOC _920554 |
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| 650 | 7 |
_aDisease resistance _2AGROVOC _91077 |
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| 650 | 7 |
_aGenetics _2AGROVOC _91130 |
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| 650 | 7 |
_aMolecular cloning _2AGROVOC _928198 |
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| 650 | 7 |
_aPlant breeding _gAGROVOC _2 _91203 |
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| 650 | 7 |
_aPlant diseases _2AGROVOC _91206 |
|
| 700 | 1 |
_aHui Chen _928199 |
|
| 700 | 0 |
_aBin Tian _928200 |
|
| 700 | 1 |
_aSehgal, S.K. _924226 |
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| 700 | 1 |
_aSingh, L.K. _91492 |
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| 700 | 0 |
_aJingzhong Xie _916451 |
|
| 700 | 1 |
_aRawat, N. _928201 |
|
| 700 | 1 |
_aJULIANA P. _8001710082 _gFormerly Global Wheat Program _gFormerly BISA _92690 |
|
| 700 | 0 |
_aNarinder Singh _98704 |
|
| 700 | 1 |
_aShrestha, S. _98259 |
|
| 700 | 1 |
_aWilson, D.L. _93981 |
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| 700 | 1 |
_aShult, H. _928202 |
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| 700 | 1 |
_aLee, H. _928203 |
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| 700 | 1 |
_aSchoen, A.W. _928204 |
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| 700 | 1 |
_aTiwari, V.K. _924296 |
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| 700 | 1 |
_aSingh, R.P. _8INT0610 _9825 _gGlobal Wheat Program |
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| 700 | 1 |
_aGuttieri, M.J. _928205 |
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| 700 | 1 |
_aTrick, H.N. _928206 |
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| 700 | 1 |
_aPoland, J.A. _92092 |
|
| 700 | 1 |
_aBowden, R.L. _93982 |
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| 700 | 0 |
_aGuihua Bai _911074 |
|
| 700 | 1 |
_aGill, B.S. _98710 |
|
| 700 | 1 |
_aLiu, S. _928207 |
|
| 773 | 0 |
_tNature Communications _gv. 13, no. 1, art. 3044 _dUnited Kingdom : Nature Publishing Group, 2022 _w57824 _x2041-1723 |
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| 856 |
_yOpen Access through DSpace _uhttps://hdl.handle.net/10883/22112 |
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| 942 |
_cJA _n0 _2ddc |
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| 999 |
_c65453 _d65445 |
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