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022 _a2044-6055 (Online)
024 8 _ahttp://dx.doi.org/10.1136/bmjopen-2014-006385
040 _aMX-TxCIM
041 _aeng
100 1 _aAfshin, A.
_925891
245 1 4 _aThe impact of dietary habits and metabolic risk factors on cardiovascular and diabetes mortality in countries of the Middle East and North Africa in 2010 :
_ba comparative risk assessment analysis
260 _aUnited Kingdom :
_bBMJ Publishing Group,
_c2015.
500 _aPeer review
500 _aOpen Access
520 _aObjective/design We conducted a comparative risk assessment analysis to estimate the cardiometabolic disease (CMD) mortality attributable to 11 dietary and 4 metabolic risk factors in 20 countries of the Middle East by age, sex and time. The national exposure distributions were obtained from a systematic search of multiple databases. Missing exposure data were estimated using a multilevel Bayesian hierarchical model. The aetiological effect of each risk factor on disease-specific mortality was obtained from clinical trials and observational studies. The number of disease-specific deaths was obtained from the 2010 Global Burden of Disease mortality database. Mortality due to each risk factor was determined using the population attributable fraction and total number of disease-specific deaths. Setting/population Adult population in the Middle East by age, sex, country and time. Results Suboptimal diet was the leading risk factor for CMD mortality in 11 countries accounting for 48% (in Morocco) to 72% (in the United Arab Emirates) of CMD deaths. Non-optimal systolic blood pressure was the leading risk factor for CMD deaths in eight countries causing 45% (in Bahrain) to 68% (in Libya) of CMD deaths. Non-optimal body mass index and fasting plasma glucose were the third and fourth leading risk factors for CMD mortality in most countries. Among individual dietary factors, low intake of fruits accounted for 8% (in Jordan) to 21% (in Palestine) of CMD deaths and low intake of whole grains was responsible for 7% (in Palestine) to 22% (in the United Arab Emirates) of CMD deaths. Between 1990 and 2010, the CMD mortality attributable to most risk factors had decreased except for body mass index and trans-fatty acids. Conclusions Our findings highlight key similarities and differences in the impact of the dietary and metabolic risk factors on CMD mortality in the countries of the Middle East and inform priorities for policy measures to prevent CMD.
546 _aText in English
650 7 _aDiet
_95374
_2AGROVOC
650 7 _aCardiovascular diseases
_920222
_2AGROVOC
650 7 _aDiabetes
_97612
_2AGROVOC
650 7 _aRisk assessment
_92007
_2AGROVOC
651 7 _2AGROVOC
_95477
_aMiddle East
651 7 _2AGROVOC
_94695
_aNorth Africa
700 1 _aMicha, R.
_925892
700 1 _aKhatibzadeh, S.
_925893
700 1 _aFahimi, S.
_925894
700 0 _aPeilin Shi
_925895
700 1 _aPowles, J.
_925896
700 1 _aSingh, G.
_925897
700 1 _aYakoob, M.Y.
_925898
700 1 _aAbdollahi, M.
_925899
700 1 _aAl-Hooti, S.
_925900
700 1 _aFarzadfar, F.
_915166
700 1 _aHoushiar-rad, A.
_925901
700 1 _aHwalla, N.
_925902
700 1 _aKoksal, E.
_925903
700 1 _aMusaiger, A.
_925904
700 1 _aPekcan, G.
_925905
700 1 _aSibai, A.M.
_925906
700 1 _aZaghloul, S.
_925907
700 1 _aDanaei, G.
_925908
700 1 _aEzzati, M.
_914829
700 1 _aMozaffarian, D.
_925909
773 0 _gv. 5, e006385
_dUnited Kingdom : BMJ Publishing Group, 2015.
_x2044-6055
_tBMJ Open
856 4 _uhttp://dx.doi.org/10.1136/bmjopen-2014-006385
_yClick here to access online
942 _cJA
_n0
_2ddc
999 _c64701
_d64693