000			02790nab|a22003617a|4500
001			64666
003			MX-TxCIM
005			20211217225745.0
008			211206s2018 xxu||||| |||| 00| 0 eng d
022			_a1932-6203 (Online)
024	8		_ahttps://doi.org/10.1371/journal.pone.0207755
040			_aMX-TxCIM
041			_aeng
100	1		_aEmbaby, A.M. _925948
245	1	0	_aMonascus orange and red pigments production by Monascus purpureus ATCC16436 through co-solid state fermentation of corn cob and glycerol : _ban eco-friendly environmental low cost approach
260			_aSan Francisco, CA (USA) : _bPublic Library of Science _c2018.
500			_aPeer review
500			_aOpen Access
520			_aThe present study underlines a statistically optimized, low cost, effective approach for efficient co-valorization of two non-efficiently utilized, highly accumulated, raw agro-industrial wastes: corn cob and glycerol for co-production of natural biopigments: monascus orange and red pigments by the aid of Monascus purpureus strain ATCC 16436. A three step sequential, statistical modeling approach: one variable at a time (OVAT), Plackett-Burman design (PBD), and central composite design (CCD) was employed to optimize the production of monascus pigments using co-solid state fermentation of the two raw agro-industrial wastes. Corn cob among other carbon sources (e.g., rice grains, sugarcane bagasse, and potato peel) was the most appropriate substrate triggering co-production of orange and red monascus pigments; deduced from OVAT. Glycerol and inoculum size proved to impose significant consequences (P<0.05) on the production of monascus pigments as inferred from PBD. The optimal levels of inoculum size (12 x 1011 spores/mL) and glycerol (2.17 M) did achieve a maximal color value of 133.77 and 108.02 color value units/mL of orange and red pigments, respectively at 30 oC after 10 days; concluded from CCD with an agitation speed of 150 rpm. Present data would underpin the large scale production of monascus pigments using the present approach for efficient exploitation of such biopigments in food, pharmaceutical and textile industries.
546			_aText in English
650		7	_aPigments _2AGROVOC _914020
650		7	_aGlycerol _2AGROVOC _913573
650		7	_aMaize _2AGROVOC _91173
650		7	_aFermentation _2AGROVOC _912531
650		7	_aGlucose _2AGROVOC _922525
650		7	_aRice _2AGROVOC _91243
650		7	_aSugar cane _2AGROVOC _96640
700	1		_aHussein, M.N. _925949
700	1		_aHussein, A. _925950
773	0		_tPLoS ONE _gv. 13, no. 12, e0207755 _dSan Francisco, CA (USA) : Public Library of Science, 2018. _x1932-6203 _wG94957
856	4		_yClick here to access online _uhttps://doi.org/10.1371/journal.pone.0207755
942			_cJA _n0 _2ddc
999			_c64666 _d64658