000			03196nab|a22004937a|4500
001			64518
003			MX-TxCIM
005			20230816210010.0
008			202101s2022||||xxk|||p|op||||00||0|eng|d
022			_a0028-646X
022			_a1469-8137 (Online)
024	8		_ahttps://doi.org/10.1111/nph.17808
040			_aMX-TxCIM
041			_aeng
100	0		_aXiuling Tian _95092
245	1	0	_aRht24b, an ancient variation of TaGA2ox-A9, reduces plant height without yield penalty in wheat
260			_aUnited Kingdom : _bWiley, _c2022.
500			_aPeer review
520			_aRht-B1b and Rht-D1b, the ‘Green Revolution’ (GR) genes, greatly improved yield potential of wheat under nitrogen fertilizer application, but reduced coleoptile length, seedling vigor and grain weight. Thus, mining alternative reduced plant height genes without adverse effects is urgently needed. We isolated the causal gene of Rht24 through map-based cloning and characterized its function using transgenic, physiobiochemical and transcriptome assays. We confirmed genetic effects of the dwarfing allele Rht24b with an association analysis and also traced its origin and distribution. Rht24 encodes a gibberellin (GA) 2-oxidase, TaGA2ox-A9. Rht24b conferred higher expression of TaGA2ox-A9 in stems, leading to a reduction of bioactive GA in stems but an elevation in leaves at the jointing stage. Strikingly, Rht24b reduced plant height, but had no yield penalty; it significantly increased nitrogen use efficiency, photosynthetic rate and the expression of related genes. Evolutionary analysis demonstrated that Rht24b first appeared in wild emmer and was detected in more than half of wild emmer and wheat accessions, suggesting that it underwent both natural and artificial selection. These findings uncover an important genetic resource for wheat breeding and also provide clues for dissecting the regulatory mechanisms underlying GA-mediated morphogenesis and yield formation.
546			_aText in English
650		7	_aGibberellins _2AGROVOC _912705
650		7	_aOxidoreductases _2AGROVOC _911420
650		7	_aGrain _2AGROVOC _91138
650		7	_aPlant height _2AGROVOC _924787
650		7	_aGenes _2AGROVOC _93563
650		7	_aWheat _2AGROVOC _91310
700	0		_aXianchun Xia _9377
700	0		_aDengan Xu _95904
700	0		_aYongqiang Liu _924788
700	0		_aLi Xie _95902
700	1		_aHassan, M.A. _97723
700	0		_aJie Song _919337
700	0		_aFaji Li _97622
700	0		_aDesen Wang _95906
700	0		_aYong Zhang _91857
700	1		_aYuanfeng Hao _gGlobal Wheat Program _8INT3329 _9919
700	0		_aGenying Li _95949
700	0		_aChengcai Chu _919338
700	1		_aHe Zhonghu _gGlobal Wheat Program _8INT2411 _9838
700	0		_aShuanghe Cao _95093
773	0		_tNew Phytologist _dUnited Kingdom : Wiley, 2022. _x1469-8137 _gv. 233, no. 2, p. 738-750 _wGu444626
942			_cJA _n0 _2ddc
999			_c64518 _d64510