000			02989nab|a22004337a|4500
999			_c63621 _d63613
001			63620
003			MX-TxCIM
005			20231009164120.0
008			202101s2020||||sz |||p|op||||00||0|eng|d
022			_a1422-0067 (Online)
024	8		_ahttps://doi.org/10.3390/ijms21239280
040			_aMX-TxCIM
041			_aeng
100	0		_aJingyang Tong _919596
245	1	0	_aDissection of molecular processes and genetic architecture underlying iron and zinc homeostasis for biofortification : _bfrom model plants to common wheat
260			_aBasel (Switzerland) : _bMDPI, _c2020.
500			_aPeer review
500			_aOpen Access
520			_aThe micronutrients iron (Fe) and zinc (Zn) are not only essential for plant survival and proliferation but are crucial for human health. Increasing Fe and Zn levels in edible parts of plants, known as biofortification, is seen a sustainable approach to alleviate micronutrient deficiency in humans. Wheat, as one of the leading staple foods worldwide, is recognized as a prioritized choice for Fe and Zn biofortification. However, to date, limited molecular and physiological mechanisms have been elucidated for Fe and Zn homeostasis in wheat. The expanding molecular understanding of Fe and Zn homeostasis in model plants is providing invaluable resources to biofortify wheat. Recent advancements in NGS (next generation sequencing) technologies coupled with improved wheat genome assembly and high-throughput genotyping platforms have initiated a revolution in resources and approaches for wheat genetic investigations and breeding. Here, we summarize molecular processes and genes involved in Fe and Zn homeostasis in the model plants Arabidopsis and rice, identify their orthologs in the wheat genome, and relate them to known wheat Fe/Zn QTL (quantitative trait locus/loci) based on physical positions. The current study provides the first inventory of the genes regulating grain Fe and Zn homeostasis in wheat, which will benefit gene discovery and breeding, and thereby accelerate the release of Fe- and Zn-enriched wheats.
526			_aWC _cFP2
546			_aText in English
591			_aYuanfeng Hao : No CIMMYT Affiliation
650		7	_aIron _2AGROVOC _93544
650		7	_aTrace elements _2AGROVOC _95624
650		7	_aGenes _2AGROVOC _93563
650		7	_aWheat _gAGROVOC _2 _91310
650		7	_aZinc _2AGROVOC _91315
700	0		_aMengjing Sun _919597
700	0		_aYue Wang _910965
700	0		_aYong Zhang _91857
700	1		_aAwais Rasheed _gGlobal Wheat Program _8I1706474 _91938
700	0		_aMing Li _914174
700	0		_aXianchun Xia _9377
700	1		_aHe Zhonghu _gGlobal Wheat Program _8INT2411 _9838
700	1		_aYuanfeng Hao _9919 _8INT3329 _gGlobal Wheat Program
773	0		_tInternational Journal of Molecular Sciences _dBasel (Switzerland) : MDPI, 2020. _x1422-0067 _gv. 21, no. 23, art. 9280 _w57216
856	4		_yOpen Access through DSpace _uhttps://hdl.handle.net/10883/21487
942			_cJA _n0 _2ddc