| 000 | 02878nab|a22003977a|4500 | ||
|---|---|---|---|
| 999 |
_c63144 _d63136 |
||
| 001 | 63144 | ||
| 003 | MX-TxCIM | ||
| 005 | 20211006085219.0 | ||
| 008 | 202102s2020||||xxk|||p|op||||00||0|eng|d | ||
| 022 | _a0031-9317 | ||
| 022 | _a1399-3054 (Online) | ||
| 024 | 8 | _ahttps://doi.org/10.1111/ppl.13260 | |
| 040 | _aMX-TxCIM | ||
| 041 | _aeng | ||
| 100 | 1 |
_aKamal, K.Y. _917975 |
|
| 245 | 1 | 0 | _aModulation of cell cycle progression and chromatin dynamic as tolerance mechanisms to salinity and drought stress in maize |
| 260 |
_aUnited Kingdom : _bWiley, _c2020. |
||
| 500 | _aPeer review | ||
| 520 | _aSalinity and drought are the major abiotic stresses that disturb several aspects of maize plants growth at the cellular level, one of these aspects is cell cycle machinery. In our study, we dissected the molecular alterations and downstream effectors of salinity and drought stress on cell cycle regulation and chromatin remodeling. Effects of salinity and drought stress were determined on maize seedlings using 200 mM NaCl (induced salinity stress), and 250 mM mannitol (induced drought stress) treatments, then cell cycle progression and chromatin remodeling dynamics were investigated. Seedlings displayed severe growth defects, including inhibition of root growth. Interestingly, stress treatments induced cell cycle arrest in S‐phase with extensive depletion of cyclins B1 and A1. Further investigation of gene expression profiles of cell cycle regulators showed the downregulation of the CDKA, CDKB, CYCA, and CYCB. These results reveal the direct link between salinity and drought stress and cell cycle deregulation leading to a low cell proliferation rate. Moreover, abiotic stress alters chromatin remodeling dynamic in a way that directs the cell cycle arrest. We observed low DNA methylation patterns accompanied by dynamic histone modifications that favor chromatin decondensation. Also, the high expression of DNA topoisomerase 2, 6 family was detected as consequence of DNA damage. In conclusion, in response to salinity and drought stress, maize seedlings exhibit modulation of cell cycle progression, resulting in the cell cycle arrest through chromatin remodeling. | ||
| 546 | _aText in English | ||
| 650 | 0 |
_aCell cycle _913512 _gAGROVOC |
|
| 650 | 7 |
_aChromatin _2AGROVOC _914145 |
|
| 650 | 7 |
_aSalinity _2AGROVOC _98901 |
|
| 650 | 7 |
_aDrought stress _2AGROVOC _91081 |
|
| 650 | 7 |
_aTolerance _2AGROVOC _94711 |
|
| 650 | 7 |
_aMaize _gAGROVOC _2 _91173 |
|
| 700 | 1 |
_aKhodaeiaminjan, M. _917976 |
|
| 700 | 1 |
_aYahya, G. _917977 |
|
| 700 | 1 |
_aEl‐Tantawy, A.A. _917978 |
|
| 700 | 1 |
_aEl‐Moneim, D.A. _917979 |
|
| 700 | 1 |
_aEl‐Esawi, M.A. _917964 |
|
| 700 | 1 |
_aAbd‐Elaziz, M.A.A. _917980 |
|
| 700 | 1 |
_aNassrallah, A.A. _917981 |
|
| 773 | 0 |
_gIn press _dUnited Kingdom : Wiley, 2020. _x0031-9317 _tPhysiologia Plantarum _wu444664 |
|
| 942 |
_cJA _n0 _2ddc |
||