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008 200520s2020||||xxu|||p|op||||00||0|eng|d
022 _a1055-7903
024 8 _ahttps://doi.org/10.1016/j.ympev.2020.106848
040 _aMX-TxCIM
041 _aeng
100 0 _aZhen He
_910981
245 1 0 _aGenetic changes and host adaptability in sugarcane mosaic virus based on complete genome sequences
260 _aUSA :
_bElsevier,
_c2020.
500 _aPeer review
520 _aSugarcane mosaic virus (SCMV), a member of the genus Potyvirus in the family Potyviridae, is an important pathogen that causes mosaic diseases in maize, sugarcane, canna and other graminaceous species worldwide. Previously, several reports have showed the genetic variation and population structure of SCMV. However, the evolutionary dynamics, synonymous codon usage pattern and adaptive evolution of the virus is unclear. In this study, we performed comprehensive analyses of phylodynamics, composition bias and codon usage of SCMV using 108 complete genomic sequences. Our phylogenetic analysis found six host- and geographically confined phylogenetic lineages within the SCMV non-recombinant isolates. We found a relatively stable and conserved genomic composition with a lower codon usage choice in the SCMV protein coding sequences. Mutation pressure and natural selection have shaped the codon usage patterns of the SCMV protein coding sequences with natural selection being the dominant factor. The codon adaptation index (CAI), relative codon deoptimization index (RCDI) and similarity index (SiD) analyses revealed a stronger correlation between SCMV and maize than between SCMV and sugarcane or canna. Our study is the first to evaluate the codon usage pattern of SCMV based on complete sequences and may provide a better understanding of the origin of SCMV and its evolutionary patterns for future research.
546 _aText in English
650 7 _2AGROVOC
_912079
_aSugarcane mosaic virus
650 7 _2AGROVOC
_913402
_aCodons
650 7 _2AGROVOC
_913403
_aNatural selection
650 7 _2AGROVOC
_913404
_aHosts
700 0 _aZhuozhuo Dong
_913405
700 0 _aHaifeng Gan
_913406
773 0 _tMolecular Phylogenetics and Evolution
_gv. 149, art. 106848
_dUSA : Elsevier, 2020.
_x1055-7903
942 _cJA
_n0
_2ddc