000			nab a22 7a 4500
999			_c60446 _d60438
001			60446
003			MX-TxCIM
005			20190607173046.0
008			190520s2006 ne |||p|op||| 00| 0 eng d
022			_a1438-4639
024	8		_ahttps://doi.org/10.1016/j.ijheh.2006.02.002
040			_aMX-TxCIM
041			_aeng
100	1		_99346 _aJolly, P.
245	1	0	_aDeterminants of aflatoxin levels in Ghanaians : _bsociodemographic factors, knowledge of aflatoxin and food handling and consumption practices
260			_aNetherlands : _bElsevier, _c2006.
500			_aPeer review
520			_aAflatoxins are among the most potent of carcinogens found in staple foods such as groundnuts, maize and other oil seeds. This study was conducted to measure the levels of aflatoxin B1 (AFB1) albumin adducts in blood and aflatoxin M1 (AFM1) metabolite in urine of people in a heavy peanut and maize consuming region of Ghana and to examine the association between aflatoxin levels and several socio-demographic factors and food handling and consumption practices. A cross-sectional study was conducted in four villages in the Ejura Sekyedumase district of Ghana. A socio-demographic survey was administered to 162 participants. Blood samples were collected from 140 and urine samples from 91 of the participants and AFB1 albumin-adduct levels in blood and AFM1 levels in urine were measured. High AFB1 albumin-adduct levels were found in the plasma (mean±SD=0.89±0.46 pmol/mg albumin; range=0.12–3.00 pmol/mg; median=0.80 pmol/mg) and high AFM1 levels in the urine (mean±SD=1,800.14±2602.01 pg/mg creatinine; range=non-detectable to 11,562.36 pg/mg; median=472.67 pg/mg) of most of the participants. There was a statistically significant correlation (; ) between AFB1–albumin adduct levels in plasma and AFM1 levels in urine. Several socio-demographic factors, namely, educational level, ethnic group, the village in which participants lived, number of individuals in the household, and number of children in the household attending secondary school, were found to be significantly associated with AFB1 albumin-adduct levels by bivariate analysis. By multivariate analyses, ethnic group (), the village in which participants live (), and the number of individuals in the household (), were significant predictors of high AFB1 albumin-adducts. These findings indicate strongly that there is need for specifically targeted post-harvest and food handling and preparation interventions designed to reduce aflatoxin exposure among the different ethnic groups in this region of Ghana.
546			_aText in English
650		7	_2AGROVOC _95637 _aAflatoxins
650		7	_2AGROVOC _96625 _aFood consumption
650		7	_2AGROVOC _99347 _aFood handling
651		7	_2AGROVOC _94493 _aGhana
700	0		_99348 _aYi Jiang
700	1		_99349 _aEllis, W.
700	1		_96767 _aAwuah, R.T.
700	1		_99350 _aNnedu, O.N,
700	1		_99351 _aPhillips, T.D.
700	0		_99352 _aJia-Sheng Wang
700	1		_99353 _aAfriyie-Gyawu, E.
700	1		_99355 _aTang, L.
700	1		_99356 _aPerson, S.
700	1		_99357 _aWilliams, J.
700	1		_99358 _aJolly, C.
773	0		_dNetherlands : Elsevier, 2006. _gv. 209, n. 4, p. 345-358 _tInternational Journal of Hygiene and Environmental Health _x1438-4639
856	4		_uhttp://libcatalog.cimmyt.org/download/reprints/60446.pdf _yAccess only for CIMMYT Staff
942			_2ddc _cJA _n0