000			03169nab a22003257a 4500
001			60160
003			MX-TxCIM
005			20230203185523.0
008			151130s2018 xxu|||p|op||| 00| 0 eng d
024	8		_ahttps://doi.org/10.3389/fgene.2018.00027
040			_aMX-TxCIM
041			_aeng
100	1		_93632 _aJighly, A.
245	1	0	_aDecomposing additive genetic variance revealed novel insights into trait evolution in synthetic hexaploid wheat
260			_aSwitzerland : _bFrontiers, _c2018.
500			_aPeer review
500			_aOpen access
520			_aWhole genome duplication (WGD) is an evolutionary phenomenon, which causes significant changes to genomic structure and trait architecture. In recent years, a number of studies decomposed the additive genetic variance explained by different sets of variants. However, they investigated diploid populations only and none of the studies examined any polyploid organism. In this research, we extended the application of this approach to polyploids, to differentiate the additive variance explained by the three subgenomes and seven sets of homoeologous chromosomes in synthetic allohexaploid wheat (SHW) to gain a better understanding of trait evolution after WGD. Our SHW population was generated by crossing improved durum parents (Triticum turgidum; 2n = 4x = 28, AABB subgenomes) with the progenitor species Aegilops tauschii (syn Ae. squarrosa, T. tauschii; 2n = 2x = 14, DD subgenome). The population was phenotyped for 10 fungal/nematode resistance traits as well as two abiotic stresses. We showed that the wild D subgenome dominated the additive effect and this dominance affected the A more than the B subgenome. We provide evidence that this dominance was not inflated by population structure, relatedness among individuals or by longer linkage disequilibrium blocks observed in the D subgenome within the population used for this study. The cumulative size of the three homoeologs of the seven chromosomal groups showed a weak but significant positive correlation with their cumulative explained additive variance. Furthermore, an average of 69% for each chromosomal group's cumulative additive variance came from one homoeolog that had the highest explained variance within the group across all 12 traits. We hypothesize that structural and functional changes during diploidization may explain chromosomal group relations as allopolyploids keep balanced dosage for many genes. Our results contribute to a better understanding of trait evolution mechanisms in polyploidy, which will facilitate the effective utilization of wheat wild relatives in breeding.
546			_aText in English
650		7	_91146 _aHexaploids _2AGROVOC
650		7	_92020 _aHexaploidy _2AGROVOC
650		7	_aWheat _2AGROVOC _91310
650		7	_91385 _aGenetic variance _2AGROVOC
700	1		_93631 _aJoukhadar, R.
700	1		_9892 _aSukhwinder-Singh _8INT3098 _gGenetic Resources Program
700	1		_9237 _aOgbonnaya, F.C.
773	0		_x1664-8021 _tFrontiers in Genetics _gv. 9, art. 27
856	4		_yOpen Access through DSpace _uhttps://hdl.handle.net/10883/19986
942			_2ddc _cJA _n0
999			_c60160 _d60152