000			03311nab a22003617a 4500
999			_c58968 _d58960
001			58968
003			MX-TxCIM
005			20211006082416.0
008			171219s2017 xxu|||p|op||| 00| 0 eng d
024	8		_ahttps://doi.org/10.3389/fpls.2017.01389
040			_aMX-TxCIM
041			_aeng
100	0		_93035 _aWeie Wen
245	1	0	_aA high-density consensus map of common wheat integrating four mapping populations scanned by the 90k SNP Array
260			_aSwitzerland : _bFrontiers, _c2017.
500			_aPeer review
500			_aOpen Access
520			_aA high-density consensus map is a powerful tool for gene mapping, cloning and molecular marker-assisted selection in wheat breeding. The objective of this study was to construct a high-density, single nucleotide polymorphism (SNP)-based consensus map of common wheat (Triticum aestivum L.) by integrating genetic maps from four recombinant inbred line populations. The populations were each genotyped using the wheat 90K Infinium iSelect SNP assay. A total of 29,692 SNP markers were mapped on 21 linkage groups corresponding to 21 hexaploid wheat chromosomes, covering 2,906.86 cM, with an overall marker density of 10.21 markers/cM. Compared with the previous maps based on the wheat 90K SNP chip detected 22,736 (76.6%) of the SNPs with consistent chromosomal locations, whereas 1,974 (6.7%) showed different chromosomal locations, and 4,982 (16.8%) were newly mapped. Alignment of the present consensus map and the wheat expressed sequence tags (ESTs) Chromosome Bin Map enabled assignment of 1,221 SNP markers to specific chromosome bins and 819 ESTs were integrated into the consensus map. The marker orders of the consensus map were validated based on physical positions on the wheat genome with Spearman rank correlation coefficients ranging from 0.69 (4D) to 0.97 (1A, 4B, 5B, and 6A), and were also confirmed by comparison with genetic position on the previously 40K SNP consensus map with Spearman rank correlation coefficients ranging from 0.84 (6D) to 0.99 (6A). Chromosomal rearrangements reported previously were confirmed in the present consensus map and new putative rearrangements were identified. In addition, an integrated consensus map was developed through the combination of five published maps with ours, containing 52,607 molecular markers. The consensus map described here provided a high-density SNP marker map and a reliable order of SNPs, representing a step forward in mapping and validation of hromosomal locations of SNPs on the wheat 90K array. Moreover, it can be used as a reference for quantitative trait loci (QTL) mapping to facilitate exploitation of genes and QTL in wheat breeding.
526			_aWC _cFP2
546			_aText in English
650		7	_91296 _aTriticum aestivum _2AGROVOC
650		7	_92084 _aChromosome mapping _2AGROVOC
700	1		_aHe Zhonghu _gGlobal Wheat Program _8INT2411 _9838
700	0		_93034 _aFengmei Gao
700	0		_93031 _aHui Jin
700	0		_93032 _aJindong Liu
700	0		_93029 _aShengnan Zhai
700	0		_95806 _aYanying Qu
700	0		_9377 _aXianchun Xia
773	0		_wu56875 _x1664-462X _dSwitzerland : Frontiers _tFrontiers in Plant Science _gv. 8, art. 1389
856	4		_yOpen Access through DSpace _uhttps://hdl.handle.net/10883/19106
942			_2ddc _cJA _n0