000 03405nab a22003977a 4500
999 _c58908
_d58900
001 58908
003 MX-TxCIM
005 20211006082127.0
008 151020s2017 sz |||p|op||| 00| 0 eng d
024 8 _ahttps://doi.org/10.3389/fpls.2017.01800
040 _aMX-TxCIM
041 _aeng
100 1 _92608
_aCrespo-Herrera, L.A.
_gGlobal Wheat Program
_8I1706538
245 1 0 _aQTL mapping of grain Zn and Fe concentrations in two hexaploid wheat RIL populations with ample transgressive segregation
_h[Electronic Resource]
260 _aSwitzerland :
_bFrontiers,
_c2017.
500 _aPeer review
500 _aOpen Access
520 _aMore than 50% of undernourished children live in Asia and more than 25% live in Africa. Coupled with an inadequate food supply, mineral deficiencies are widespread in these populations; particularly zinc (Zn) and iron (Fe) deficiencies that lead to retarded growth, adverse effects on both the immune system and an individual's cognitive abilities. Biofortification is one solution aimed at reducing the incidence of these deficiencies. To efficiently breed a biofortified wheat variety, it is important to generate knowledge of the genomic regions associated with grain Zn (GZn) and Fe (GFe) concentration. This allows for the introgression of favorable alleles into elite germplasm. In this study we evaluated two bi-parental populations of 188 recombinant inbred lines (RILs) displaying a significant range of transgressive segregation for GZn and GFe during three crop cycles in CIMMYT, Mexico. Parents of the RILs were derived from Triticum spelta L. and synthetic hexaploid wheat crosses. QTL analysis identified a number of significant QTL with a region denominated as QGZn.cimmyt-7B_1P2 on chromosome 7B explaining the largest (32.7%) proportion of phenotypic variance (PVE) for GZn and leading to an average additive effect of −1.3. The QTL with the largest average additive effect for GFe (−0.161) was found on chromosome 4A (QGFe.cimmyt-4A_P2), with 21.14% of the PVE. The region QGZn.cimmyt-7B_1P2 co-localized closest to the region QGZn.cimmyt-7B_1P1 in a consensus map built from the linkage maps of both populations. Pleiotropic or tightly linked QTL were also found on chromosome 3B, however of minor effects and PVE between 4.3 and 10.9%. Further efforts are required to utilize the QTL information in marker assisted backcrossing schemes for wheat biofortification. A strategy to follow is to intercross the transgressive individuals from both populations and then utilize them as sources in biofortification breeding pipelines.
526 _aWC
526 _aA4N8H
546 _aText in English
591 _aYuanfeng Hao : No CIMMYT Affiliation
650 7 _91853
_aQuantitative Trait Loci
_2AGROVOC
650 7 _aWheat
_gAGROVOC
_2
_91310
650 7 _91315
_aZinc
_2AGROVOC
650 7 _93544
_aIron
_2AGROVOC
650 7 _92020
_aHexaploidy
_2AGROVOC
650 7 _98866
_aSegregation
_2AGROVOC
700 1 _9880
_aVelu, G.
_8INT2983
_gGlobal Wheat Program
700 1 _92027
_aStangoulis, J.
700 1 _9919
_aYuanfeng Hao
_8INT3329
_gGlobal Wheat Program
700 1 _aSingh, R.P.
_gGlobal Wheat Program
_8INT0610
_9825
773 0 _wu56875
_x1664-462X
_dSwitzerland : Frontiers
_tFrontiers in Plant Science
_gv. 8, art. 1800
856 4 _yOpen Access through DSpace
_uhttps://hdl.handle.net/10883/19103
942 _2ddc
_cJA
_n0