000			02626nab a22003497a 4500
999			_c56923 _d56915
001			56923
003			MX-TxCIM
005			20201204192523.0
008			150722s2015 xxu|||p|op||| 00| 0 eng d
024	8		_ahttps://doi.org/10.1534/g3.114.016022
040			_aMX-TxCIM
100	1		_91387 _aLuyan Zhang
245	1		_aLinkage analysis and map construction in genetic populations of clonal F1 and double cross
260			_aBethesda, MD : _bGenetics Society of America, _c2015.
500			_aOpen Access
500			_aPeer review
520			_aIn this study, we considered four categories of molecular markers based on the number of distinguishable alleles at the marker locus and the number of distinguishable genotypes in clonal F1 progenies. For two marker loci, there are nine scenarios that allow the estimation of female, male, and/ or combined recombination frequencies. In a double cross population derived from four inbred lines, five categories of markers are classified and another five scenarios are present for recombination frequency estimation. Theoretical frequencies of identifiable genotypes were given for each scenario, from which the maximum likelihood estimates of one or more of the three recombination frequencies could be estimated. If there was no analytic solution, then Newton-Raphson method was used to acquire a numerical solution. We then proposed to use an algorithm in Traveling Salesman Problem to determine the marker order. Finally, we proposed a procedure to build the two haploids of the female parent and the two haploids of the male parent in clonal F1. Once the four haploids were built, clonal F1 hybrids could be exactly regarded as a double cross population. Efficiency of the proposed methods was demonstrated in simulated clonal F1 populations and one actual maize double cross. Extensive comparisons with software JoinMap4.1, OneMap, and R/qtl show that the methodology proposed in this article can build more accurate linkage maps in less time.
536			_aGenetic Resources Program
546			_aText in english
591			_bCIMMYT Informa No. 1944
594			_aCLIH01
594			_aINT2542
650		0	_91390 _aClonal F1
650	1	0	_91393 _aDouble cross
650		0	_91394 _aLinkage analysis
650		7	_92084 _aChromosome mapping _2AGROVOC
650		7	_98955 _aClones _2AGROVOC
650		7	_94190 _aGenetic maps _2AGROVOC
650		7	_98632 _aRecombinant DNA _2AGROVOC
650		7	_91848 _aGenetic markers _2AGROVOC
700	1		_9764 _aHuihui Li _gGenetic Resources Program _8CLIH01
700	1		_9842 _aJiankang Wang _gGenetic Resources Program _8INT2542
773	0		_wu56922 _x2160-1836 _dBethesda, MD : Genetics Society of America, 2011- _tG3: Genes, Genomes, Genetics _gv. 5, no. 3, p. 427-439
856	4		_yOpen Access through DSpace _uhttp://hdl.handle.net/10883/4537
942			_2ddc _cJA _n0