000			03571nab a22004697a 4500
001			G95016
003			MX-TxCIM
005			20240919020946.0
008			210621s2012 ne |||p|op||| 00| 0 eng d
022			_a1572-9788 (Online)
022			_a1380-3743
024	8		_ahttps://doi.org/10.1007/s11032-011-9569-7
040			_aMX-TxCIM
041			_aeng
090			_aCIS-6623
100	1		_9851 _aDreisigacker, S. _gGlobal Wheat Program _8INT2692
245	1	0	_aGenetic structures of the CIMMYT international yield trial targeted to irrigated environments
260			_aDordrecht (Netherlands) : _bSpringer, _c2012.
500			_aPeer review
500			_aPeer-review: Yes - Open Access: Yes|http://science.thomsonreuters.com/cgi-bin/jrnlst/jlresults.cgi?PC=MASTER&ISSN=1380-3743
520			_aInternational yield trials are assembled by CIMMYT to disseminate promising wheat breeding materials worldwide. To assess the genomic structure and linkage disequilibrium (LD) within this germplasm, wheat lines disseminated during 25 years of the Elite Spring Wheat Yield Trial (ESWYT) targeted for irrigated environments of the world were genotyped with the high-throughput Diversity Arrays Technology (DArT) marker system. Analyses of population structure assigned the ESWYT germplasm into five major sub-populations that are shaped by prominent CIMMYT wheat lines and their descendants. Based on genetic distance, we concluded that a constant level of genetic diversity was maintained over the years of ESWYT dissemination. Genetic distance between the individual ESWYT lines significantly increased when the ESWYT were grouped according to the differences in years of ESWYT dissemination, suggesting a systematic change in allele frequencies over time, most probably due to breeding and directional selection. By means of multiple regression analyses, 78 markers displaying a significant change in allele frequency across years were identified and interpreted as an indicator for constant selection. The markers identified were partly associated with grain yield, leaf, stem, and yellow rust and point to key genomic regions for further investigation. Large numbers of adjacent DArT marker pairs showed significant LD across the ESWYT population and within each of the five sub-populations identified. Sub-population differentiation measured by the fixation index and average genetic distance were highly correlated with LD levels, suggesting that the sub-populations themselves explain much of the LD.
536			_aGenetic Resources Program|Global Wheat Program
546			_aText in English
591			_aCIMMYT Informa No. 1782
594			_aINT0599|CCJL01|INT2692|INT0610
595			_aCSC
650		7	_aYields _2AGROVOC _91313
650		7	_aExperimentation _2AGROVOC _94432
650		7	_aPopulation Structure _2AGROVOC _98720
650		7	_aGenetic diversity (as resource) _2AGROVOC _92974
650		7	_aLinkage disequilibrium _2AGROVOC _924205
700	1		_920476 _aShewayrga, H.
700	1		_aCrossa, J. _gGenetic Resources Program _8CCJL01 _959
700	1		_91426 _aArief, V.N.
700	1		_91427 _aDeLacy, I.H.
700	1		_aSingh, R.P. _gGlobal Wheat Program _8INT0610 _9825
700	1		_aDieters, M.J.J. _8001712805 _gExcellence in Breeding _91430
700	1		_aBraun, H.J. _gFormerly Global Wheat Program _8INT0599 _9824
773	0		_tMolecular Breeding _gv. 29, no. 2, p. 529-541 _dDordrecht (Netherlands) : Springer, 2012. _wG78961 _x1380-3743
856	4		_uhttps://hdl.handle.net/20.500.12665/573 _yAccess only for CIMMYT Staff
942			_cJA _2ddc _n0
999			_c28379 _d28379