000			02902nab a22003977a 4500
001			G90560
003			MX-TxCIM
005			20230904155046.0
008			210702s2008 ne |||p|op||| 00| 0 eng d
022			_a1572-9788 (Online)
022			_a1380-3743
024	8		_ahttps://doi.org/10.1007/s11032-008-9157-7
040			_aMX-TxCIM
041			_aeng
090			_aCIS-5352
100	1		_aHanda, H. _91970
245	1	0	_aDissecting of the FHB resistance QTL on the short arm of wheat chromosome 2D using a comparative genomic approach : _bfrom QTL to candidate gene
260			_aDordrecht (Netherlands) : _bSpringer, _c2008.
340			_aComputer File|Printed
500			_aPeer review
500			_aPeer-review: Yes - Open Access: Yes|http://science.thomsonreuters.com/cgi-bin/jrnlst/jlresults.cgi?PC=MASTER&ISSN=1380-3743
520			_aColinearity in gene content and order between rice and closely related cereal crops has been a powerful tool for gene identification. Using a comparative genomic approach, we have identified the rice genomic region syntenous to the region of the short arm of wheat chromosome 2D, on which quantitative trait loci (QTLs) for Fusarium head blight (FHB) resistance and for controlling accumulation of the mycotoxin deoxynivalenol (DON) are closely located. Utilizing markers known to reside near the FHB resistance QTL and data from several wheat genetic maps, we have limited the syntenous region to 6.8 Mb of the short arm of rice chromosome 4. From the 6.8-Mb sequence of rice chromosome 4, we found three putative rice genes that could have a role in detoxification of mycotoxins. DNA sequences of these putative rice genes were used in BLAST searches to identify wheat expressed sequence tags (ESTs) exhibiting significant similarity. Combined data from expression analysis and gene mapping of wheat homologues and results of analysis of DON accumulation using doubled haploid populations revealed that a putative gene for multidrug resistance-associated protein (MRP) is a possible candidate for the FHB resistance and/or DON accumulation controlling QTLs on wheat chromosome 2DS and can be used as a molecular marker to eliminate the susceptible allele when the Chinese wheat variety Sumai 3 is used as a resistance source.
546			_aText in English
650		7	_aWheat _2AGROVOC _91310
650		7	_aQuantitative Trait Loci _2AGROVOC _91853
650		7	_aFusarium _2AGROVOC _92705
650		7	_aBlight _2AGROVOC _95348
650		7	_aGenomics _2AGROVOC _91132
650		7	_aMycotoxins _2AGROVOC _92377
700	0		_aNobukazu Namiki _920819
700	0		_aDonghe Xu _920820
700	0		_aBan Tomohiro _920784
773	0		_tMolecular Breeding _n635295 _gv. 22, no. 1, p. 71-84 _dDordrecht (Netherlands) : Springer, 2008. _wG78961 _x1380-3743
856	4		_yAccess only for CIMMYT Staff _uhttps://hdl.handle.net/20.500.12665/716
942			_cJA _2ddc _n0
999			_c27074 _d27074