000 01629nab a22002417a 4500
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022 _aNo (Revista en electrónico)
040 _aMX-TxCIM
090 _aREP-12963
100 1 _aMackay, I.
245 0 0 _aMethods for linkage disequilibrium mapping in crops
260 _c2007
340 _aComputer File|Printed
500 _aPeer-review: Yes - Open Access: Yes|http://science.thomsonreuters.com/cgi-bin/jrnlst/jlresults.cgi?PC=MASTER&ISSN=1360-1385
520 _aLinkage disequilibrium (LD) mapping in plants detects and locates quantitative trait loci (QTL) by the strength of the correlation between a trait and a marker. It offers greater precision in QTL location than family-based linkage analysis and should therefore lead to more efficient marker-assisted selection, facilitate gene discovery and help to meet the challenge of connecting sequence diversity with heritable phenotypic differences. Unlike family-based linkage analysis, LD mapping does not require family or pedigree information and can be applied to a range of experimental and non-experimental populations. However, care must be taken during analysis to control for the increased rate of false positive results arising from population structure and variety interrelationships. In this review, we discuss how suitable the recently developed alternative methods of LD mapping are for crops.
546 _aEnglish
700 1 _aPowell, W.,
_ecoaut.
773 0 _tTrends in Plant Science
_n634940
_gv. 12, no. 2, p. 57-63
942 _cJA
_2ddc
999 _c26886
_d26886