000 01942nab a22004217a 4500
001 a54093
003 MX-TxCIM
005 20170719155107.0
008 121211b |||p||p||||||| |z||| |
022 0 _a0021-8812
040 _aMX-TxCIM
041 0 _aEn
043 _aUS
072 0 _aL74
082 0 4 _a93-119086
100 1 _aSmith, T.K.
245 0 0 _aRecent advances in the understanding of Fusarium trichothecene mycotoxicoses
260 _c1992
340 _aPrinted
500 _aPeer-review: Yes - Open Access: Yes|http://science.thomsonreuters.com/cgi-bin/jrnlst/jlresults.cgi?PC=MASTER&ISSN=0021-8812
500 _areferences. Paper presented at a symposium entitled "Current Perspectives on Mycotoxins in Animal Feeds," Laramie, WY. Literature review
520 _aRecent concepts in the etiology of Fusarium trichothecene mycotoxicoses have been reviewed. The effect of orally administered trichothecenes on tissue metabolism has been traced from the gastrointestinal tract to the liver and subsequently to blood. It is proposed that the hyperaminoacidemia resulting from trichothecene toxicoses contributes to the behavioral changes observed, including loss of appetite and vomiting. Studies with several species and several trichothecenes have shown that elevated brain tryptophan arising from trichothecene-induced aminoacidemia can subsequently alter regional brain serotonin concentrations. This may produce
546 _aEnglish
591 _aUS (DNAL 49 J82)|COMOD
595 _aAC
650 1 0 _aANIMAL MORPHOLOGY
650 1 0 _aCentral nervous system
650 1 0 _aDeuteromycotina
650 1 0 _aDigestive system
650 1 0 _aFungi
_91121
650 1 0 _aMiscellaneous animal disorders
650 1 0 _aMycotoxins
_92377
650 1 0 _aNervous system
650 1 0 _aToxic substances
650 1 0 _aToxins
773 0 _tJournal of Animal Science
_n93-119086
_gv. 70, no. 12, p. 3989-3993
942 _cJA
999 _c16371
_d16371