TY  - JA
AU  - Bingyan Liu
AU  - Mengjing Sun
AU  - Ke Wang
AU  - Yingjie Bian
AU  - Yuqing Che
AU  - Jindong Liu
AU  - Xumei Luo
AU  - Siyang Liu
AU  - Lina Xie
AU  - Lingli Li
AU  - Kejia Qu
AU  - Yuheng Chao
AU  - Rui Che
AU  - Xingguo Ye
AU  - Xianchun Xia
AU  - Long Mao
AU  - He Zhonghu
AU  - Aili Li
AU  - Shuanghe Cao
TI  - Wheat domestication gene Q interplays with TaARF12 to antagonistically modulate plant architecture by integrating multiple hormone homeostasis
SN  - 0028-646X
PY  - 2025///
CY  - United Kingdom
PB  - New Phytologist Foundation, 
KW  - Wheat
KW  - AGROVOC
KW  - Yield potential
KW  - Domestication
KW  - Genes
KW  - Homeostasis
N1  - Peer review
N2  - Wheat domestication gene Q controls threshability and also pleiotropically affects plant morphogenesis. However, its specific roles in modulating plant architecture and the underlying mechanisms remain unclear. We dissected Q effects on plant architecture using transgenic overexpression and knockout assays. The analyses of micromorphological and dynamic imaging, physiological productivity, multi-omics, and molecular interaction were performed to dissect the underlying regulatory mechanism. Allelic variation and genetic effect assays were employed to identify desirable haplotypes. The domesticated Q allele 5AQ in wild-type lines optimized plant architecture and endowed yield gain by modulating cell size of stem internodes and flag leaves, tiller initiation and outgrowth, and photosynthetic capacity. Q regulated many homologs of previously reported functional genes controlling plant architecture, multiple hormone homeostasis, and cell wall components. Q upregulated plant architecture regulators TaARF12-2B and TaARF12-2D by binding to the promoters. However, Q and the TaARF12 genes antagonistically modulate plant architecture. The favorable haplotypes of TaARF12-2B and the functional variation site were identified, and their origin, spread, and distribution were also traced. These findings specify the Q function in controlling plant architecture and yield formation, broaden insights into the underlying mechanism, and provide new molecular tools for wheat improvement
DO  - https://doi.org/10.1111/nph.70487
T2  - New Phytologist
ER  -