TY  - JA
AU  - Ying Ding
AU  - Hongliang Wu
AU  - Na Ning
AU  - Haiyue Yu
AU  - Chaotian Liu
AU  - Ruoya Lv
AU  - Shu Li
AU  - Junjie Hao
AU  - Xintao Wang
AU  - Xuecai Zhang
AU  - Xin Xie
AU  - Xinfeng Li
AU  - Wende Liu
AU  - Zhiqiang Li
TI  - Histone ZmH2B regulates resistance to the Southern corn leaf blight pathogen Bipolaris maydis in maize
SN  - 1471-2229
PY  - 2025///
CY  - United Kingdom
PB  - BioMed Central Ltd,, 
KW  - Maize
KW  - AGROVOC
KW  - Cochliobolus heterostrophus
KW  - Transcriptome
KW  - Biotic stress
N1  - Peer review; Open Access
N2  - Background: H2B histones play crucial roles in plant responses to biotic stress. However, to date, most research on H2B histones has focused on their roles in post-translational modification, and studies specifically investigating the intrinsic properties of these histones remain relatively limited. Here we identified the ZmH2B in maize (Zea mays) and investigated its role in the response of maize to infection by the Southern corn leaf blight pathogen Bipolaris maydis. Result: In this study, a nucleus-localized ZmH2B was identified from maize. To characterize the role of this histone in disease resistance, we employed virus-induced gene silencing (VIGS) and transient overexpression (VOX) to generate ZmH2B-silenced (FoMV:ZmH2B) and ZmH2B-overexpressing (FoMV:ZmH2B-VOX) lines. FoMV:ZmH2B lines showed enhanced B. maydis infection and an inhibited chitin-induced reactive oxygen species burst, whereas FoMV:ZmH2B-VOX lines exhibited the opposite effects. Furthermore, ZmH2B overexpression induced the expression of various pathogenesis-related genes, suggesting that these genes enhance resistance against B. maydis. Transcriptome analysis of ZmH2B-silenced plants revealed that the differentially expressed genes were predominantly enriched in photosynthesis-related pathways, pointing to a role for photosynthesis in B. maydis resistance. Conclusions: These results suggest that ZmH2B positively regulates maize resistance to B. maydis
UR  - https://hdl.handle.net/10883/35900
T2  - BMC Plant Biology
DO  - https://doi.org/10.1186/s12870-025-07020-9
ER  -