TY - JA AU - Montesinos-Lopez,O.A. AU - Crossa,J. AU - Vitale,P. AU - Gerard,G.S. AU - Crespo-Herrera,L.A. AU - Dreisigacker,S. AU - Saint Pierre,C. AU - Posadas,L.G. AU - Agbona,A. AU - Buenrostro-Mariscal,R. AU - Montesinos-Lopez,A. AU - Chawade,A. TI - GBLUP outperforms quantile mapping and outlier detection for enhanced genomic prediction SN - 1422-0067 PY - 2025/// CY - Switzerland PB - MDPI, KW - Marker-assisted selection KW - AGROVOC KW - Plant breeding KW - Forecasting KW - Wheat N1 - Peer review; Open Access N2 - Genomic selection (GS) accelerates plant breeding by predicting complex traits using genomic data. This study compares genomic best linear unbiased prediction (GBLUP), quantile mapping (QM)-an adjustment to GBLUP predictions-and four outlier detection methods. Using 14 real datasets, predictive accuracy was evaluated with Pearson's correlation (COR) and normalized root mean square error (NRMSE). GBLUP consistently outperformed all other methods, achieving an average COR of 0.65 and an NRMSE reduction of up to 10% compared to alternative approaches. The proportion of detected outliers was low (<7%), and their removal had minimal impact on GBLUP's predictive performance. QM provided slight improvements in datasets with skewed distributions but showed no significant advantage in well-distributed data. These findings confirm GBLUP's robustness and reliability, suggesting limited utility for QM when data deviations are minimal UR - https://hdl.handle.net/10883/35640 DO - https://doi.org/10.3390/ijms26083620 T2 - International Journal of Molecular Sciences ER -