TY - JA AU - Ce Deng AU - Leonard,A. AU - Cahill,J. AU - Meng Lv AU - Yurong Li AU - Thatcher,S. AU - Xueying Li AU - Xiaodi Zhao AU - Wenjie Du AU - Zheng Li AU - Huimin Li AU - Llaca,V. AU - Fengler,K. AU - Marshall,L. AU - Harris,C. AU - Tabor,G. AU - Zhimin Li AU - Zhiqiang Tian AU - Qinghua Yang AU - Yanhui Chen AU - Jihua Tang AU - Xintao Wang AU - Junjie Hao AU - Jianbing Yan AU - Zhibing Lai AU - Xiaohong Fei AU - Weibin Song AU - Jinsheng Lai AU - Xuecai Zhang AU - Guoping Shu AU - Yibo Wang AU - Yuxiao Chang AU - Weiling Zhu AU - Wei Xiong AU - Sun,J. AU - Bailin Li AU - TI - The RppC-AvrRppC NLR-effector interaction mediates the resistance to southern corn rust in maize SN - 16742052 PY - 2022/// CY - USA PB - Cell Press, KW - Maize KW - AGROVOC KW - Rusts KW - Zea mays KW - Plant diseases KW - Yield losses N1 - Peer review; Corrected Proof N2 - Southern corn rust (SCR), caused by the fungal pathogen Puccinia polysora, is a major threat to maize production worldwide. Efficient breeding and deployment of resistant hybrids are key to achieving durable control of SCR. Here, we report the molecular cloning and characterization of RppC, which encodes an NLR-type immune receptor and is responsible for a major SCR resistance quantitative trait locus. Furthermore, we identified the corresponding avirulence effector, AvrRppC, which is secreted by P. polysora and triggers RppC-mediated resistance. Allelic variation of AvrRppC directly determines the effectiveness of RppC-mediated resistance, indicating that monitoring of AvrRppC variants in the field can guide the rational deployment of RppC-containing hybrids in maize production. Currently, RppC is the most frequently deployed SCR resistance gene in China, and a better understanding of its mode of action is critical for extending its durability DO - https://doi.org/10.1016/j.molp.2022.01.007 T2 - Molecular Plant ER -