TY - JA AU - Gaurav,K. AU - Sanu Arora AU - Silva,P. AU - Sánchez-Martín,J. AU - Horsnell,R. AU - Liangliang Gao AU - Brar,G.S. AU - Widrig,V. AU - Raupp,W.J. AU - Narinder Singh AU - Shuangye Wu AU - Sandip Kale AU - Chinoy,C. AU - Nicholson,P. AU - Quiroz-Chávez,J. AU - Simmonds,J. AU - Hayta,S. AU - Smedley,M.A. AU - Harwood,W. AU - Pearce,S. AU - Gilbert,D. AU - Ngonidzashe Kangara AU - Gardener,C. AU - Forner-Martínez,M. AU - Jiaqian Liu AU - Guotai Yu AU - Boden,S.A. AU - Pascucci,A. AU - Ghosh,S. AU - Hafeez,A.N. AU - O’Hara,T. AU - Waites,J.O. AU - Cheema,J. AU - Steuernagel,B. AU - Patpour,M. AU - Justesen,A.F. AU - Shuyu Liu AU - Rudd,J.C. AU - Avni,R. AU - Sharon,A. AU - Steiner,B. AU - Kirana,R.P. AU - Buerstmayr,H. AU - Mehrabi,A.A. AU - Nasyrova,F.Y. AU - Chayut,N. AU - Matny,O. AU - Steffenson,B.J. AU - Sandhu,N. AU - Chhuneja, P. AU - Lagudah,E.S. AU - Elkot,A.F. AU - Tyrrell,S. AU - Xingdong Bian AU - Davey,R.P. AU - Simonsen,M. AU - Schauser,L. AU - Tiwari,V.K. AU - Kutcher,H.R. AU - Hucl,P.J. AU - Aili Li AU - Dengcai Liu AU - Long Mao AU - Xu,S. AU - Brown-Guedira,G. AU - Faris,J. AU - Dvorak,J. AU - Ming-Cheng Luo AU - Krasileva,K. AU - Lux,T. AU - Artmeier,S. AU - Mayer,K.F.X. AU - Uauy,C. AU - Mascher,M. AU - Bentley,A.R. AU - Keller,B. AU - Poland,J.A. AU - Wulff,B.B.H TI - Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement SN - 1087-0156 PY - 2022/// CY - United Kingdom PB - Nature Publishing Group KW - Population genetics KW - AGROVOC KW - Aegilops KW - Plant breeding KW - Crop improvement KW - Soft wheat N1 - Peer review; Open Access N2 - Aegilops tauschii, the diploid wild progenitor of the D subgenome of bread wheat, is a reservoir of genetic diversity for improving bread wheat performance and environmental resilience. Here we sequenced 242 Ae. tauschii accessions and compared them to the wheat D subgenome to characterize genomic diversity. We found that a rare lineage of Ae. tauschii geographically restricted to present-day Georgia contributed to the wheat D subgenome in the independent hybridizations that gave rise to modern bread wheat. Through k-mer-based association mapping, we identified discrete genomic regions with candidate genes for disease and pest resistance and demonstrated their functional transfer into wheat by transgenesis and wide crossing, including the generation of a library of hexaploids incorporating diverse Ae. tauschii genomes. Exploiting the genomic diversity of the Ae. tauschii ancestral diploid genome permits rapid trait discovery and functional genetic validation in a hexaploid background amenable to breeding UR - https://hdl.handle.net/10883/21731 T2 - Nature Biotechnology DO - https://doi.org/10.1038/s41587-021-01058-4 ER -