TY  - JA
AU  - Xiuling Tian
AU  - Xianchun Xia
AU  - Dengan Xu
AU  - Yongqiang Liu
AU  - Li Xie
AU  - Hassan,M.A.
AU  - Jie Song 
AU  - Faji Li
AU  - Desen Wang
AU  - Yong Zhang
AU  - Yuanfeng Hao
AU  - Genying Li
AU  - Chengcai Chu
AU  - He Zhonghu
AU  - Shuanghe Cao
TI  - Rht24b, an ancient variation of TaGA2ox-A9, reduces plant height without yield penalty in wheat
SN  - 0028-646X
PY  - 2022///
CY  - United Kingdom
PB  - Wiley
KW  - Gibberellins
KW  - AGROVOC
KW  - Oxidoreductases
KW  - Grain
KW  - Plant height
KW  - Genes
KW  - Wheat
N1  - Peer review
N2  - Rht-B1b and Rht-D1b, the ‘Green Revolution’ (GR) genes, greatly improved yield potential of wheat under nitrogen fertilizer application, but reduced coleoptile length, seedling vigor and grain weight. Thus, mining alternative reduced plant height genes without adverse effects is urgently needed. We isolated the causal gene of Rht24 through map-based cloning and characterized its function using transgenic, physiobiochemical and transcriptome assays. We confirmed genetic effects of the dwarfing allele Rht24b with an association analysis and also traced its origin and distribution. Rht24 encodes a gibberellin (GA) 2-oxidase, TaGA2ox-A9. Rht24b conferred higher expression of TaGA2ox-A9 in stems, leading to a reduction of bioactive GA in stems but an elevation in leaves at the jointing stage. Strikingly, Rht24b reduced plant height, but had no yield penalty; it significantly increased nitrogen use efficiency, photosynthetic rate and the expression of related genes. Evolutionary analysis demonstrated that Rht24b first appeared in wild emmer and was detected in more than half of wild emmer and wheat accessions, suggesting that it underwent both natural and artificial selection. These findings uncover an important genetic resource for wheat breeding and also provide clues for dissecting the regulatory mechanisms underlying GA-mediated morphogenesis and yield formation
DO  - https://doi.org/10.1111/nph.17808
T2  - New Phytologist
ER  -