TY  - JA
AU  - Hambidge,K.M.
AU  - Garcia,O.P.
AU  - Gonzalez,K.
AU  - Hotz,C.
AU  - Krebs,N.F.
AU  - Miller,L.V.
AU  - Pfeiffer,W.
AU  - Rosado,J.L.
AU  - Westcott,J.E.
AU  - Ortiz-Monasterio,I.
TI  - Absorption of zinc (Zn) from high Zn and control wheat
PY  - 2008///
N1  - Peer-review: Yes - Open Access: Yes|http://science.thomsonreuters.com/cgi-bin/jrnlst/jlresults.cgi?PC=MASTER&ISSN=0892-6638
N2  - Background: One goal of HarvestPlus is to increase the Zn content of crops by selective plant breeding. The objective of this study was to assess the efficacy of moderately high-Zn wheat by measuring Zn absorption from a quantity of wheat (300 g) likely to be consumed daily by adult women who depend on wheat as a major food staple. Study Design: Randomized double blind cross-over design within extraction groups (95% and 80%). 28 healthy women were randomized to consume tortillas prepared from either high or control Zn wheat on day 1 or 2 as their primary source of energy and Zn. Total absorbed Zn (TAZ, mg) from high Zn wheat tortillas was compared with control wheat tortillas and with the predicted TAZ from a model of TAZ as a function of total ingested Zn (TIZ, mg) and phytate (TIP, mg) at 2 extraction levels. TIZ was measured by extrinsic labeling with stable Zn isotopes and a dual isotope tracer ratio technique. Salient data, means (SD), are given in the table. Conclusion: A significant increase in TAZ is achieved with selection of moderately high Zn wheat. The increase in absorbed Zn is compatible with that predicted from a model of TAZ as a function of TIZ and TIP. Variation in extraction between 95% and 80% does not alter TAZ. Supported by HarvestPlus & IAEA
T2  - FASEB Journal
ER  -