Knowledge Center Catalog

Marker assisted selection: is it practical?

By: Contributor(s): Material type: TextTextPublication details: Montevideo (Uruguay) CIMMYT : 2000Description: 103-110ISBN:
  • 9974-7586-1-0
Subject(s): DDC classification:
  • 633.1153 KOH
Summary: Molecular markers have been proposed for use in fingerprinting, parental selection, monitoring homozygosity; outcrossing, or genetic stocks, for selection of loci controlling traits that are difficult or costly to evaluate, or have low heritability; and for selection against donor genome in backcrosses. The use of markers for these activities to date has been minimal, especially for crops such as wheat where the genetic system is complex. There are many potential problems. Some of the limitations include low polymorphism, complex inheritance, low precision in mapping, errors in assigning relative weights or in choosing loci, cost of developing and using molecular markers, undetected recombination between markers and trait loci, unknown linkage relationships between marker and trait alleles in genotypes other than parents of mapping populations, locus x year interaction, and negative pleiotropic effects. Because conventional breeding methods have been effective for improving quantitative traits, there is resistance to implementation of marker assisted selection due to labor and cost. Initially; marker assisted selection (MAS) in backcross populations using elite recurrent parents is the most efficient method for testing the efficacy of MAS. For species with low polymorphism, the use of hypervariable markers such as microsatellites is critical.
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Item type Current library Collection Call number Copy number Status Date due Barcode Item holds
Conference proceedings CIMMYT Knowledge Center: John Woolston Library CIMMYT Publications Collection 633.1153 KOH (Browse shelf(Opens below)) 1 Available E649448
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Molecular markers have been proposed for use in fingerprinting, parental selection, monitoring homozygosity; outcrossing, or genetic stocks, for selection of loci controlling traits that are difficult or costly to evaluate, or have low heritability; and for selection against donor genome in backcrosses. The use of markers for these activities to date has been minimal, especially for crops such as wheat where the genetic system is complex. There are many potential problems. Some of the limitations include low polymorphism, complex inheritance, low precision in mapping, errors in assigning relative weights or in choosing loci, cost of developing and using molecular markers, undetected recombination between markers and trait loci, unknown linkage relationships between marker and trait alleles in genotypes other than parents of mapping populations, locus x year interaction, and negative pleiotropic effects. Because conventional breeding methods have been effective for improving quantitative traits, there is resistance to implementation of marker assisted selection due to labor and cost. Initially; marker assisted selection (MAS) in backcross populations using elite recurrent parents is the most efficient method for testing the efficacy of MAS. For species with low polymorphism, the use of hypervariable markers such as microsatellites is critical.

English

0105|AL-Wheat Program|AGRIS 0102

Jose Juan Caballero

CIMMYT Publications Collection


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