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Absorption of zinc (Zn) from high Zn and control wheat

By: Contributor(s): Material type: ArticleArticlePublication details: 2008 In: FASEB Journal v. 22, p. 149.5Summary: Background: One goal of HarvestPlus is to increase the Zn content of crops by selective plant breeding. The objective of this study was to assess the efficacy of moderately high-Zn wheat by measuring Zn absorption from a quantity of wheat (300 g) likely to be consumed daily by adult women who depend on wheat as a major food staple. Study Design: Randomized double blind cross-over design within extraction groups (95% and 80%). 28 healthy women were randomized to consume tortillas prepared from either high or control Zn wheat on day 1 or 2 as their primary source of energy and Zn. Total absorbed Zn (TAZ, mg) from high Zn wheat tortillas was compared with control wheat tortillas and with the predicted TAZ from a model of TAZ as a function of total ingested Zn (TIZ, mg) and phytate (TIP, mg) at 2 extraction levels. TIZ was measured by extrinsic labeling with stable Zn isotopes and a dual isotope tracer ratio technique. Salient data, means (SD), are given in the table. Conclusion: A significant increase in TAZ is achieved with selection of moderately high Zn wheat. The increase in absorbed Zn is compatible with that predicted from a model of TAZ as a function of TIZ and TIP. Variation in extraction between 95% and 80% does not alter TAZ. Supported by HarvestPlus & IAEA.
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Peer-review: Yes - Open Access: Yes|http://science.thomsonreuters.com/cgi-bin/jrnlst/jlresults.cgi?PC=MASTER&ISSN=0892-6638

Background: One goal of HarvestPlus is to increase the Zn content of crops by selective plant breeding. The objective of this study was to assess the efficacy of moderately high-Zn wheat by measuring Zn absorption from a quantity of wheat (300 g) likely to be consumed daily by adult women who depend on wheat as a major food staple. Study Design: Randomized double blind cross-over design within extraction groups (95% and 80%). 28 healthy women were randomized to consume tortillas prepared from either high or control Zn wheat on day 1 or 2 as their primary source of energy and Zn. Total absorbed Zn (TAZ, mg) from high Zn wheat tortillas was compared with control wheat tortillas and with the predicted TAZ from a model of TAZ as a function of total ingested Zn (TIZ, mg) and phytate (TIP, mg) at 2 extraction levels. TIZ was measured by extrinsic labeling with stable Zn isotopes and a dual isotope tracer ratio technique. Salient data, means (SD), are given in the table. Conclusion: A significant increase in TAZ is achieved with selection of moderately high Zn wheat. The increase in absorbed Zn is compatible with that predicted from a model of TAZ as a function of TIZ and TIP. Variation in extraction between 95% and 80% does not alter TAZ. Supported by HarvestPlus & IAEA.

Conservation Agriculture Program

English

Lucia Segura

INT1421

CIMMYT Staff Publications Collection


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