Identification of O-methylsterigmatocystin as an aflatoxin B1 and G1 precursor in Aspergillus parasiticus
Material type:
ArticleLanguage: En Publication details: 1987ISSN: - 1098-5336 (Revista en electrónico)
- 0099-2240
| Item type | Current library | Collection | Call number | Copy number | Status | Date due | Barcode | Item holds | |
|---|---|---|---|---|---|---|---|---|---|
| Article | CIMMYT Knowledge Center: John Woolston Library | Reprints Collection | REP-4160 (Browse shelf(Opens below)) | 1 | Available | 617559 |
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Peer-review: Yes - Open Access: Yes|http://science.thomsonreuters.com/cgi-bin/jrnlst/jlresults.cgi?PC=MASTER&ISSN=0099-2240
Tables, graphs, literture cited p. 1032-1033
An isolate of A. parasiticus CP461 (SRRC 2043) produced no detectable aflatoxins, but accumulated O-methylsterigmatocystin (OMST). When sterigmatocystin (ST) was fed to this isolate in a low-sugar medium, there was an increase in the accumulation of OMST, without aflatoxin synthesis. When radiolabelled [14C]OMST was fed to resting mycelia of a non-aflatoxin-, non-ST-,and non-OMST-producing mutant of A. parasiticus AVN-1 (SRRC 163), 14C-labelled aflatoxins B1 and G1 were produced; 10 nmol of OMST produced 7.8 nmol of B1 and 1 nmol of G1, while 10 nmol of ST produced 6.4 nmol of B1 and 0.6 nmol of G1. A time course study of aflatoxin synthesis in ST feeding
English
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