The separation of epistatic from additive and dominance variation in generation means.
Material type: ArticleLanguage: English Publication details: 1958. United Kingdom : Springer Nature,ISSN:- 0018-067X
- ISSN 1365-2540 (Online)
Item type | Current library | Collection | Call number | Copy number | Status | Date due | Barcode | Item holds | |
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Article | CIMMYT Knowledge Center: John Woolston Library | Reprints Collection | REP-833 (Browse shelf(Opens below)) | 1 | Available | 601023 |
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Peer-review: Yes - Open Access: Yes|http://science.thomsonreuters.com/cgi-bin/jrnlst/jlresults.cgi?PC=MASTER&ISSN=0018-067X
MATHER (1949) introduced tests of generation means for epistasis which were elaborated by Cavalli (1952), Anderson and Kempthorne (1954),Jinks (1956) and Hayman (1957). Models of certain epistatic systems were described by Griffing (1950), Powers (1951) and Homer, Comstock and Robinson (1955). More general models were developed by Anderson and Kempthorne (1954), Hayman (1954a) and Hayman and Mather (1955) to describe the genetic variation present in twoinbred lines and their descendant families. Anderson and Kempthorne showed in particular that all the information about additive, dominance and digenic epistatic variation available in the means of generations descended from two inbred lines is contained in just six parameters. Here we describe the estimation from various experiments of sixrelated parameters. We discover whether any useful measures of epistasis exist and investigate the problem of separating additive anddominance effects from epistatic effects.
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