Comparing wMAS, GWAS, and genomic prediction for selecting powdery mildew-resistant spring barley genotypes (Record no. 69735)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03339nab|a22004097a|4500 |
| 001 - CONTROL NUMBER | |
| control field | 69735 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-TxCIM |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260107133341.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 202512s2025||||-uk|||p|op||||00||0|eng|d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1471-2164 |
| 024 8# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | https://doi.org/10.1186/s12864-025-12395-y |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MX-TxCIM |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Su Myat Noe |
| 9 (RLIN) | 39576 |
| 245 10 - TITLE STATEMENT | |
| Title | Comparing wMAS, GWAS, and genomic prediction for selecting powdery mildew-resistant spring barley genotypes |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | London (United Kingdom) : |
| Name of publisher, distributor, etc. | BioMed Central Ltd., |
| Date of publication, distribution, etc. | 2025. |
| 500 ## - GENERAL NOTE | |
| General note | Peer review |
| 500 ## - GENERAL NOTE | |
| General note | Open Access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Barley is one of the most widely cultivated cereals worldwide, and powdery mildew is among the major diseases threatening global barley production. Our study evaluated 370 spring barley breeding lines under controlled greenhouse growth conditions. Results: Using genome-wide association study (GWAS), 21 quantitative trait loci (QTL) were identified associated with seedling-stage powdery mildew resistance. Of these, eight were newly identified in this study. Genetic merit was also calculated using major-effect markers, and a positive correlation (> 0.7) was observed between the genetic merit and BLUP (AUDPC) values in both the two subpopulations of two- and six-row barley. While evaluating the performance of genomic prediction (GP) models, a GWAS-incorporated GP model consistently outperformed the Standard GP model in both subpopulations demonstrating the advantage of incorporating major-effect markers for a more accurate prediction. Our analysis of genotype selection patterns revealed a notable degree of agreement among the tested methods. In the two-row subpopulation, a large number of genotypes were exclusively selected by weighted marker-assisted selection (wMAS) revealing the dominance of major-effect QTL. In contrast, the six-row subpopulation had a smaller wMAS-exclusive group, suggesting a more polygenic background, which was captured by genomic prediction. Additionally, genomics-based methods consistently identified resistant genotypes that were overlooked by phenotypic selection, showing their ability to detect hidden genetic potential. Conclusions: Overall, GWAS-incorporated GP model demonstrated the best performance among the evaluated methods, suggesting this approach is the most effective with a potential to contribute to efficient breeding of powdery mildew resistance in spring barley. |
| 546 ## - LANGUAGE NOTE | |
| Language note | Text in English |
| 597 ## - CGIAR Initiative | |
| Donor or Funder | Swedish University of Agricultural Sciences (SLU) |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Genome-wide association studies |
| 9 (RLIN) | 31443 |
| Source of heading or term | AGROVOC |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Marker-assisted selection |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 10737 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Genomics |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1132 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Forecasting |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 2701 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Barley |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1018 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Powdery mildews |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 5953 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Best linear unbiased predictor |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 26493 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pawan Kumar Singh |
| Miscellaneous information | Global Wheat Program |
| Field link and sequence number | INT2868 |
| 9 (RLIN) | 868 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Odilbekov, F. |
| 9 (RLIN) | 10674 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Johansson, E. |
| 9 (RLIN) | 39578 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chawade, A. |
| 9 (RLIN) | 7735 |
| 773 0# - HOST ITEM ENTRY | |
| Title | BMC Genomics |
| Related parts | v. 26, no. 1, art. 1091 |
| Place, publisher, and date of publication | London (United Kingdom) : BioMed Central Ltd., 2025. |
| International Standard Serial Number | 1471-2164 |
| Record control number | 56896 |
| 856 4# - ELECTRONIC LOCATION AND ACCESS | |
| Link text | Open Access through DSpace |
| Uniform Resource Identifier | https://hdl.handle.net/10883/36646 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Article |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Date last seen | Total Checkouts | Price effective from | Koha item type | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Withdrawn status | Home library | Current library | Date acquired |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 12/22/2025 | 12/22/2025 | Article | Not Lost | Dewey Decimal Classification | CIMMYT Staff Publications Collection | CIMMYT Knowledge Center: John Woolston Library | CIMMYT Knowledge Center: John Woolston Library | 12/22/2025 |