Delivering trait-enhanced varieties to African smallholders through a pangenomic breeding network (Record no. 69464)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 05498nab|a22010457a|4500 |
| 001 - CONTROL NUMBER | |
| control field | 69464 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-TxCIM |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20251103130603.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 2510282025|||||xxu||p|op||||00||0|sengdd |
| 024 8# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | https://doi.org/10.1101/2025.08.07.667917 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MX-TxCIM |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Fanna Maina |
| 9 (RLIN) | 40427 |
| 245 10 - TITLE STATEMENT | |
| Title | Delivering trait-enhanced varieties to African smallholders through a pangenomic breeding network |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | Nueva York (United States of America) : |
| Name of publisher, distributor, etc. | bioRxiv, |
| Date of publication, distribution, etc. | 2025. |
| 500 ## - GENERAL NOTE | |
| General note | Preprint |
| 500 ## - GENERAL NOTE | |
| General note | Open Access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Pangenomics has been promoted to accelerate breeding of orphan crops, but smallholder farmers in developing nations have seen little benefit so far. To address this gap, we built a global pangenomic breeding network, integrating African breeding programs, U.S. land grant universities, and international nonprofit research organizations. Here we demonstrate that pangenomics, when integrated with local crop improvement knowledge and global scientific partnerships, can facilitate breeding of drought and pest resilient varieties for smallholders. To breed trait-enhanced sorghum varieties with lgs1-1 resistance to witchweed (Striga hermonthica) for smallholders in Niger, one of the world’s least developed nations, we used population genomics across local and global scales to develop lgs1-1 Striga resistance markers, and deployed them for rapid introgression of resistance into locally-preferred varieties. Genomic characterization, along with controlled experiments in laboratory, pot, field stations, and smallholder farms, confirmed lgs1-1 resistance was introgressed without loss of essential local-preference traits. New pangenomic resources, including global resequencing and graph pangenomes, further accelerated design of broadly-applicable markers. Unlocking the potential of pangenomics for stress-resilience breeding depended on stakeholder input, strong inference, South-led decision support software, and a dense collaborative network. The experience of the network provides a scalable roadmap for collaborative pangenomic breeding of trait-enhanced varieties for the world’s lowest-resourced farmers. |
| 546 ## - LANGUAGE NOTE | |
| Language note | Text in English |
| 597 ## - CGIAR Initiative | |
| Donor or Funder | United States Agency for International Development (USAID) |
| -- | Bill & Melinda Gates Foundation (BMGF) |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Varieties |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1303 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Breeding |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1029 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Smallholders |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1763 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Crop improvement |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1059 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Genomic selection |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1513 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Food security |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1118 |
| 651 #7 - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
| Geographic name | Africa |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1316 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Faye, J.M. |
| Field link and sequence number | 001714758 |
| Miscellaneous information | Dryland Crops Program |
| 9 (RLIN) | 37348 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kena, A.W. |
| 9 (RLIN) | 40428 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Diatta, C. |
| 9 (RLIN) | 37120 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Moctar Issiakou Tankari |
| 9 (RLIN) | 40429 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ousseini Abdou Ardaly |
| 9 (RLIN) | 40430 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ousmane Seyni Diakite |
| 9 (RLIN) | 40431 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Aissata Mamadou Ibrahim |
| 9 (RLIN) | 40432 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Oumarou Abdoulye Moussa |
| 9 (RLIN) | 40433 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abdou Harou |
| 9 (RLIN) | 40434 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rabiou Abdou |
| 9 (RLIN) | 40435 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pascal Sene, J. |
| 9 (RLIN) | 40436 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Souleymane Bodian |
| 9 (RLIN) | 40437 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mbery Ndour |
| 9 (RLIN) | 40438 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Diarietou Sambakhe |
| 9 (RLIN) | 40439 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bassirou Sine |
| 9 (RLIN) | 40440 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pana Kadanga |
| 9 (RLIN) | 40441 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eyanawa Akata |
| 9 (RLIN) | 40442 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ouédraogo, N. |
| 9 (RLIN) | 37125 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Annor, B. |
| 9 (RLIN) | 6789 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tetteh, I.T. |
| 9 (RLIN) | 40443 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Muhammad Ahmad Yahaya |
| 9 (RLIN) | 30038 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Abdoulaye Diallo |
| 9 (RLIN) | 37232 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kakeeto, R. |
| 9 (RLIN) | 37707 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kisilu, R. |
| 9 (RLIN) | 37122 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Clarisse Pulchérie Kondombo |
| 9 (RLIN) | 40444 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tokuma Legesse |
| 9 (RLIN) | 40445 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mbulwe, L. |
| 9 (RLIN) | 37123 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mutaliano, J. |
| 9 (RLIN) | 29688 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mwenda, E.T. |
| 9 (RLIN) | 32958 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gapili Naoura |
| 9 (RLIN) | 40446 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hortense Noëlle Apala Mafouasson |
| 9 (RLIN) | 40447 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Opare-Obuobi, K. |
| 9 (RLIN) | 40448 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rekiya Otuchu Abdulmalik |
| 9 (RLIN) | 40449 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Runo, S. |
| 9 (RLIN) | 17616 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tilal Sayed Abdelhalim |
| 9 (RLIN) | 40450 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yalaukani, L. |
| 9 (RLIN) | 37700 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Masanga, J. |
| 9 (RLIN) | 11059 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McLaughlin, C.M. |
| 9 (RLIN) | 40451 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lasky, J.R. |
| 9 (RLIN) | 9592 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Harder, A.M. |
| 9 (RLIN) | 40452 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Healey, A.L. |
| 9 (RLIN) | 40453 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lovell, J.T. |
| 9 (RLIN) | 40454 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Osei-Obeng, P. |
| 9 (RLIN) | 40455 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marla, S.R. |
| 9 (RLIN) | 40456 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Felderhoff, T.J. |
| 9 (RLIN) | 40457 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hamidou, F. |
| 9 (RLIN) | 2344 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Foncéka, D. |
| 9 (RLIN) | 26805 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chejerla, M.K.V. |
| Miscellaneous information | Dryland Crops Program |
| Field link and sequence number | 001714111 |
| 9 (RLIN) | 31909 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nebie, B. |
| Field link and sequence number | 001712983 |
| Miscellaneous information | Genetic Resources Program |
| -- | Dryland Crops Program |
| 9 (RLIN) | 30039 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tamerlane Mark Nas |
| Field link and sequence number | 001713621 |
| Miscellaneous information | Genetic Resources Program |
| -- | Dryland Crops Program |
| 9 (RLIN) | 31154 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Field link and sequence number | 001711980 |
| Personal name | Alakonya, A. |
| Miscellaneous information | Genetic Resources Program |
| -- | Dryland Crops Program |
| 9 (RLIN) | 11060 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rathore, A. |
| Field link and sequence number | 001712937 |
| Miscellaneous information | Excellence in Breeding |
| -- | Genetic Resources Program |
| 9 (RLIN) | 7897 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Deshpande, S. |
| 9 (RLIN) | 4852 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Field link and sequence number | 001712882 |
| Personal name | Gandhi, H. |
| Miscellaneous information | Genetic Resources Program |
| -- | Dryland Crops Program |
| 9 (RLIN) | 31144 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Banda, L. |
| 9 (RLIN) | 40458 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rhodes, D.H. |
| 9 (RLIN) | 4849 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cruet-Burgos, C. |
| 9 (RLIN) | 40459 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | VanGessel, C.J. |
| 9 (RLIN) | 40460 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Morris, G.P. |
| 9 (RLIN) | 4848 |
| 773 0# - HOST ITEM ENTRY | |
| Title | bioRxiv |
| Related parts | In press |
| Place, publisher, and date of publication | Nueva York (United States of America) : bioRxiv, 2025. |
| 856 4# - ELECTRONIC LOCATION AND ACCESS | |
| Link text | Open Access through DSpace |
| Uniform Resource Identifier | https://hdl.handle.net/10883/36005 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Article |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Date last seen | Total Checkouts | Price effective from | Koha item type | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Withdrawn status | Home library | Current library | Date acquired |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 10/28/2025 | 10/28/2025 | Article | Not Lost | Dewey Decimal Classification | CIMMYT Staff Publications Collection | CIMMYT Knowledge Center: John Woolston Library | CIMMYT Knowledge Center: John Woolston Library | 10/28/2025 |