Knowledge Center Catalog

An InDel insertion in the promoter of a UDP-ᴅ-glucuronate 4-epimerase 1 gene enhances maize resistance to Fusarium ear rot (Record no. 69048)

MARC details
000 -LEADER
fixed length control field 03257nab|a22005537a|4500
001 - CONTROL NUMBER
control field 69048
003 - CONTROL NUMBER IDENTIFIER
control field MX-TxCIM
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20251222172411.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 20251s2025|||||-us||p|op||||00||0|eng|dd
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2590-3462 (Online)
024 8# - OTHER STANDARD IDENTIFIER
Standard number or code https://doi.org/10.1016/j.xplc.2025.101380
040 ## - CATALOGING SOURCE
Original cataloging agency MX-TxCIM
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Chaopei Dong
9 (RLIN) 8492
245 13 - TITLE STATEMENT
Title An InDel insertion in the promoter of a UDP-ᴅ-glucuronate 4-epimerase 1 gene enhances maize resistance to Fusarium ear rot
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. United States of America :
Name of publisher, distributor, etc. Elsevier Inc. ;
-- Cell Press,
Date of publication, distribution, etc. 2025.
500 ## - GENERAL NOTE
General note Peer review
500 ## - GENERAL NOTE
General note Open Access
520 ## - SUMMARY, ETC.
Summary, etc. Fusarium ear rot (FER), caused by Fusarium verticillioides, results in substantial yield losses and poses a significant threat to maize production worldwide. However, the genetic basis of FER resistance remains poorly understood. Utilizing QTL-seq and association analysis, we identified a gene encoding UDP-ᴅ-glucuronate 4-epimerase 1 (ZmGAE1). A 141-base pair insertion was revealed as the natural functional variation in the promoter of ZmGAE1, which decreases its expression and enhances resistance to FER. Functional validation confirmed that ZmGAE1 acts as a negative regulator of maize resistance to FER. Notably, reduced ZmGAE1 accumulation not only improved FER resistance but also lowered fumonisin content. This effect was attributed to increased cell density within the down-placenta chalaza region, accompanied by the accumulation of galacturonic acid and pectin. Crucially, lines lacking ZmGAE1 exhibited no adverse effects on key agronomic traits and showed resistance to multiple diseases, including maize stalk rot, southern leaf blight, and seed rot. These findings highlight ZmGAE1 as a promising candidate for improving FER resistance in maize, offering a novel approach for crop protection and sustainable agriculture.
546 ## - LANGUAGE NOTE
Language note Text in English
591 ## - CATALOGING NOTES
Affiliation Jiafa Chen : No CIMMYT Affiliation
597 ## - CGIAR Initiative
Donor or Funder Natural Science Foundation of China (NSFC)
-- National Key Research and Development Program
Program & Accelerators Breeding for Tomorrow
CGSpace handle https://hdl.handle.net/10568/179221
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Fusarium
Source of heading or term AGROVOC
9 (RLIN) 2705
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Maize
Source of heading or term AGROVOC
9 (RLIN) 1173
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Maize stalk rot
Source of heading or term AGROVOC
9 (RLIN) 10977
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Disease resistance
Source of heading or term AGROVOC
9 (RLIN) 1077
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Yabin Wu
9 (RLIN) 8215
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Jingyang Gao
9 (RLIN) 8216
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Yunxia Song
9 (RLIN) 8217
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Zhaokun Wu
9 (RLIN) 32791
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Zhao Wang
9 (RLIN) 8486
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Jianju He
9 (RLIN) 39660
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Qian Yu
9 (RLIN) 39661
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Zhonghuan Zhao
9 (RLIN) 39662
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Mengya Cao
9 (RLIN) 39663
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Ronghui Zhang
9 (RLIN) 39664
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Weibin Song
9 (RLIN) 17443
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Xuecai Zhang
Miscellaneous information Global Maize Program
Field link and sequence number INT3400
9 (RLIN) 951
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Pei Jing
9 (RLIN) 32794
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Doudou Sun
9 (RLIN) 32793
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Huiyong Zhang
9 (RLIN) 28591
700 0# - ADDED ENTRY--PERSONAL NAME
Personal name Zijian Zhou
9 (RLIN) 8213
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Jiafa Chen
Miscellaneous information Genetic Resources Program
Field link and sequence number INT3373
9 (RLIN) 947
700 2# - ADDED ENTRY--PERSONAL NAME
Personal name Jianyu Wu
9 (RLIN) 1412
773 0# - HOST ITEM ENTRY
Title Plant Communications
Related parts v. 6, no. 7, art. 101380
Place, publisher, and date of publication United States of America : Elsevier Inc. ; Cell Press, 2025.
International Standard Serial Number 2590-3462
856 4# - ELECTRONIC LOCATION AND ACCESS
Link text Open Access through DSpace
Uniform Resource Identifier https://hdl.handle.net/10883/35800
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Article
Suppress in OPAC No
Source of classification or shelving scheme Dewey Decimal Classification
Holdings
Date last seen Total Checkouts Price effective from Koha item type Lost status Source of classification or shelving scheme Damaged status Not for loan Collection code Withdrawn status Home library Current library Date acquired
07/11/2025   07/11/2025 Article Not Lost Dewey Decimal Classification     CIMMYT Staff Publications Collection   CIMMYT Knowledge Center: John Woolston Library CIMMYT Knowledge Center: John Woolston Library 07/11/2025

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