Membrane-permeable trehalose 6-phosphate precursor spray increases wheat yields in field trials (Record no. 68789)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02901nab|a22005057a|4500 |
| 001 - CONTROL NUMBER | |
| control field | 68789 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-TxCIM |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516155500.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 20254s2025|||||-uk||p|op||||00||0|eng|dd |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1087-0156 |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1546-1696 (Online) |
| 024 8# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | https://doi.org/10.1038/s41587-025-02611-1 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MX-TxCIM |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Griffiths, C.A. |
| 9 (RLIN) | 17212 |
| 245 10 - TITLE STATEMENT | |
| Title | Membrane-permeable trehalose 6-phosphate precursor spray increases wheat yields in field trials |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | United Kingdom : |
| Name of publisher, distributor, etc. | Nature Research, |
| Date of publication, distribution, etc. | 2025. |
| 500 ## - GENERAL NOTE | |
| General note | Peer review |
| 500 ## - GENERAL NOTE | |
| General note | Open Access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Trehalose 6-phosphate (T6P) is an endogenous sugar signal in plants that promotes growth, yet it cannot be introduced directly into crops or fully genetically controlled. Here we show that wheat yields were improved using a timed microdose of a plant-permeable, sunlight-activated T6P signaling precursor, DMNB-T6P, under a variety of agricultural conditions. Under both well-watered and water-stressed conditions over 4 years, DMNB-T6P stimulated yield of three elite varieties. Yield increases were an order of magnitude larger than average annual genetic gains of breeding programs and occurred without additional water or fertilizer. Mechanistic analyses reveal that these benefits arise from increased CO2 fixation and linear electron flow ('source') as well as from increased starchy endosperm volume, enhanced grain sieve tube development and upregulation of genes for starch, amino acid and protein synthesis ('sink'). These data demonstrate a step-change, scalable technology with net benefit to the environment that could provide sustainable yield improvements of diverse staple cereal crops. |
| 546 ## - LANGUAGE NOTE | |
| Language note | Text in English |
| 597 ## - CGIAR Initiative | |
| Donor or Funder | Biotechnology and Biological Sciences Research Council (BBSRC) |
| -- | Engineering and Physical Sciences Research Council (EPSRC) |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Trehalose |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 18783 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Phosphates |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 5224 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Wheat |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1310 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Yields |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1313 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Field Experimentation |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 8629 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Xiaochao Xue |
| 9 (RLIN) | 38795 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Miret, J.A. |
| 9 (RLIN) | 38796 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Salvagiotti, F. |
| 9 (RLIN) | 38797 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Field link and sequence number | 001712527 |
| Personal name | Acevedo-Siaca L.G. |
| Miscellaneous information | Global Wheat Program |
| 9 (RLIN) | 19854 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gimeno, J. |
| Field link and sequence number | I1706704 |
| Miscellaneous information | Global Wheat Program |
| 9 (RLIN) | 4777 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Reynolds, M.P. |
| Miscellaneous information | Global Wheat Program |
| Field link and sequence number | INT1511 |
| 9 (RLIN) | 831 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hassall, K.L. |
| 9 (RLIN) | 19432 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Halsey, K. |
| 9 (RLIN) | 38798 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Puranik, S. |
| 9 (RLIN) | 18074 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Oszvald, M. |
| 9 (RLIN) | 38799 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kurup, S. |
| 9 (RLIN) | 38800 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Davis, B.G. |
| 9 (RLIN) | 38801 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Paul, M.J. |
| 9 (RLIN) | 17213 |
| 773 0# - HOST ITEM ENTRY | |
| Title | Nature Biotechnology |
| Place, publisher, and date of publication | United Kingdom : Nature Research, 2025. |
| International Standard Serial Number | 1087-0156 |
| Related parts | In press |
| 856 4# - ELECTRONIC LOCATION AND ACCESS | |
| Link text | Open Access through DSpace |
| Uniform Resource Identifier | https://hdl.handle.net/10883/35641 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Article |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Date last seen | Total Checkouts | Price effective from | Koha item type | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Withdrawn status | Home library | Current library | Date acquired |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 05/09/2025 | 05/09/2025 | Article | Not Lost | Dewey Decimal Classification | CIMMYT Staff Publications Collection | CIMMYT Knowledge Center: John Woolston Library | CIMMYT Knowledge Center: John Woolston Library | 05/09/2025 |