MARC details
| 000 -LEADER |
| fixed length control field |
03322nab|a22003737a|4500 |
| 001 - CONTROL NUMBER |
| control field |
68701 |
| 003 - CONTROL NUMBER IDENTIFIER |
| control field |
MX-TxCIM |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
| control field |
20250806111442.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
| fixed length control field |
20252s2025||||mx |||p|op||||00||0|eng|d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
| International Standard Serial Number |
2673-3439 (Online) |
| 024 8# - OTHER STANDARD IDENTIFIER |
| Standard number or code |
https://doi.org/10.3389/fgeed.2025.1542487 |
| 040 ## - CATALOGING SOURCE |
| Original cataloging agency |
MX-TxCIM |
| 041 ## - LANGUAGE CODE |
| Language code of text/sound track or separate title |
eng |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
| Personal name |
Waites, J.O. |
| Field link and sequence number |
001714540 |
| Miscellaneous information |
Genetic Resources Program |
| 9 (RLIN) |
24922 |
| 245 10 - TITLE STATEMENT |
| Title |
CRISPR-mediated genome editing of wheat for enhancing disease resistance |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
| Place of publication, distribution, etc. |
Switzerland : |
| Name of publisher, distributor, etc. |
Frontiers Media S.A., |
| Date of publication, distribution, etc. |
2025. |
| 500 ## - GENERAL NOTE |
| General note |
Peer review |
| 500 ## - GENERAL NOTE |
| General note |
Open Access |
| 520 ## - SUMMARY, ETC. |
| Summary, etc. |
Wheat is cultivated across diverse global environments, and its productivity is significantly impacted by various biotic stresses, most importantly but not limited to rust diseases, Fusarium head blight, wheat blast, and powdery mildew. The genetic diversity of modern cultivars has been eroded by domestication and selection, increasing their vulnerability to biotic stress due to uniformity. The rapid spread of new highly virulent and aggressive pathogen strains has exacerbated this situation. Three strategies can be used for enhancing disease resistance through genome editing: introducing resistance (R) gene-mediated resistance, engineering nucleotide-binding leucine-rich repeat receptors (NLRs), and manipulating susceptibility (S) genes to stop pathogens from exploiting these factors to support infection. Utilizing R gene-mediated resistance is the most common strategy for traditional breeding approaches, but the continuous evolution of pathogen effectors can eventually overcome this resistance. Moreover, modifying S genes can confer pleiotropic effects that hinder their use in agriculture. Enhancing disease resistance is paramount for sustainable wheat production and food security, and new tools and strategies are of great importance to the research community. The application of CRISPR-based genome editing provides promise to improve disease resistance, allowing access to a broader range of solutions beyond random mutagenesis or intraspecific variation, unlocking new ways to improve crops, and speeding up resistance breeding. Here, we first summarize the major disease resistance strategies in the context of important wheat diseases and their limitations. Next, we turn our attention to the powerful applications of genome editing technology in creating new wheat varieties against important wheat diseases. |
| 546 ## - LANGUAGE NOTE |
| Language note |
Text in English |
| 597 ## - CGIAR Initiative |
| CGIAR Initiative |
Genome Editing |
| Donor or Funder |
CGIAR Trust Fund |
| CGSpace handle |
https://hdl.handle.net/10568/173898 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name as entry element |
Gene editing |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
23072 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name as entry element |
Wheat |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1310 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name as entry element |
CRISPR |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
26508 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name as entry element |
Disease resistance |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1077 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Achary, V.M.M. |
| Field link and sequence number |
001713766 |
| Miscellaneous information |
Genetic Resources Program |
| 9 (RLIN) |
31158 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
| Field link and sequence number |
001714845 |
| Personal name |
David, E.S. |
| Miscellaneous information |
Genetic Resources Program |
| 9 (RLIN) |
38243 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Hearne, S. |
| Miscellaneous information |
Genetic Resources Program |
| -- |
Director General's Office |
| Field link and sequence number |
INT3287 |
| 9 (RLIN) |
912 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Bandyopadhyay, A. |
| Field link and sequence number |
001714002 |
| Miscellaneous information |
Genetic Resources Program |
| 9 (RLIN) |
25685 |
| 773 0# - HOST ITEM ENTRY |
| Title |
Frontiers in Genome Editing |
| Related parts |
v. 7, art. 1542487 |
| Place, publisher, and date of publication |
Switzerland : Frontiers Media S.A., 2025. |
| International Standard Serial Number |
2673-3439 |
| 856 4# - ELECTRONIC LOCATION AND ACCESS |
| Link text |
Open Access through DSpace |
| Uniform Resource Identifier |
https://hdl.handle.net/10883/35537 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
| Koha item type |
Article |
| Suppress in OPAC |
No |
| Source of classification or shelving scheme |
Dewey Decimal Classification |