MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03039nab|a22004697a|4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
68612 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
MX-TxCIM |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20250206143637.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
20251ss2025|||msz ||ppoop|||00||0|eengdd |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
|---|
| International Standard Serial Number |
2223-7747 (Online) |
| 024 8# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
https://doi.org/10.3390/plants14020295 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
MX-TxCIM |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Murithi, A. |
| 9 (RLIN) |
8545 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Global transcriptomic analysis of inbred lines reveal candidate genes for response to maize lethal necrosis |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
Switzerland : |
| Name of publisher, distributor, etc. |
MDPI, |
| Date of publication, distribution, etc. |
2025. |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Peer review |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Open access |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Maize lethal necrosis (MLN) is a significant threat to food security in Sub-Saharan Africa (SSA), with limited commercial inbred lines displaying tolerance. This study analyzed the transcriptomes of four commercially used maize inbred lines and a non-adapted inbred line, all with varying response levels to MLN. RNA-Seq revealed differentially expressed genes in response to infection by maize chlorotic mottle virus (MCMV) and sugarcane mosaic virus (SCMV), the causative agents of MLN. Key findings included the identification of components of the plant innate immune system, such as differentially regulated R genes (mainly LRRs), and activation/deactivation of virus resistance pathways, including RNA interference (RNAi) via Argonaute (AGO), Dicer-like proteins, and the ubiquitin–proteasome system (UPS) via RING/U-box and ubiquitin ligases. Genes associated with redox signaling, WRKY transcription factors, and cell modification were also differentially expressed. Additionally, the expression of translation initiation and elongation factors, eIF4E and eIF4G, correlated with the presence of MLN viruses. These findings provide valuable insights into the molecular mechanisms of MLN resistance and highlight potential gene candidates for engineering or selecting MLN-resistant maize germplasm for SSA. |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
Text in English |
| 591 ## - CATALOGING NOTES |
|---|
| Affiliation |
Murithi, A. : Not in IRS Staff list but CIMMYT Affiliation |
| 591 ## - CATALOGING NOTES |
|---|
| Affiliation |
Olsen, M. : Not CIMMYT Affiliation |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Disease resistance |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1077 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Gene Expression |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
8835 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Maize |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1173 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Maize chlorotic mottle virus |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
9361 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Necrosis |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1187 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
RNA Sequence |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
9041 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Sugarcane mosaic virus |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
12079 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Plant viruses |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1543 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Genetic resistance |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
2277 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Gayathri Panangipalli |
| 9 (RLIN) |
38184 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Zhengyu Wen |
| Field link and sequence number |
001712121 |
| Miscellaneous information |
Genetic Resources Program |
| 9 (RLIN) |
5758 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Olsen, M. |
| Miscellaneous information |
Global Maize Program |
| Field link and sequence number |
INT3333 |
| 9 (RLIN) |
923 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Lübberstedt, T. |
| 9 (RLIN) |
8785 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Field link and sequence number |
I1706696 |
| Personal name |
Dhugga, K. |
| Miscellaneous information |
Genetic Resource Program |
| 9 (RLIN) |
4340 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Jung, M. |
| 9 (RLIN) |
38185 |
| 773 0# - HOST ITEM ENTRY |
|---|
| Place, publisher, and date of publication |
Switzerland : MDPI, 2025. |
| Related parts |
v. 14, no. 2, art. 295 |
| Title |
Plants |
| International Standard Serial Number |
2223-7747 |
| 856 4# - ELECTRONIC LOCATION AND ACCESS |
|---|
| Link text |
Open Access through DSpace |
| Uniform Resource Identifier |
https://hdl.handle.net/10883/35474 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Article |
| Suppress in OPAC |
No |
| Source of classification or shelving scheme |
Dewey Decimal Classification |