MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03753nab|a22004937a|4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
65099 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
MX-TxCIM |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20231009164120.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
20221s22022|||msz ||p|op||||00||0|eengdd |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
|---|
| International Standard Serial Number |
1664-462X |
| 024 8# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
https://doi.org/10.3389/fpls.2022.840614 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
MX-TxCIM |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Jingyang Tong |
| 9 (RLIN) |
19596 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
High resolution genome wide association studies reveal rich genetic architectures of grain zinc and iron in common wheat (Triticum aestivum L.) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Name of publisher, distributor, etc. |
Frontiers, |
| Date of publication, distribution, etc. |
2022. |
| Place of publication, distribution, etc. |
Switzerland : |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Peer review |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Open Access |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Biofortification is a sustainable strategy to alleviate micronutrient deficiency in humans. It is necessary to improve grain zinc (GZnC) and iron concentrations (GFeC) in wheat based on genetic knowledge. However, the precise dissection of the genetic architecture underlying GZnC and GFeC remains challenging. In this study, high-resolution genome-wide association studies were conducted for GZnC and GFeC by three different models using 166 wheat cultivars and 373,106 polymorphic markers from the wheat 660K and 90K single nucleotide polymorphism (SNP) arrays. Totally, 25 and 16 stable loci were detected for GZnC and GFeC, respectively. Among them, 17 loci for GZnC and 8 for GFeC are likely to be new quantitative trait locus/loci (QTL). Based on gene annotations and expression profiles, 28 promising candidate genes were identified for Zn/Fe uptake (8), transport (11), storage (3), and regulations (6). Of them, 11 genes were putative wheat orthologs of known Arabidopsis and rice genes related to Zn/Fe homeostasis. A brief model, such as genes related to Zn/Fe homeostasis from root uptake, xylem transport to the final seed storage was proposed in wheat. Kompetitive allele-specific PCR (KASP) markers were successfully developed for two major QTL of GZnC on chromosome arms 3AL and 7AL, respectively, which were independent of thousand kernel weight and plant height. The 3AL QTL was further validated in a bi-parental population under multi-environments. A wheat multidrug and toxic compound extrusion (MATE) transporter TraesCS3A01G499300, the ortholog of rice gene OsPEZ2, was identified as a potential candidate gene. This study has advanced our knowledge of the genetic basis underlying GZnC and GFeC in wheat and provides valuable markers and candidate genes for wheat biofortification. |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
Text in English |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Biofortification |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1731 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Iron |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
3544 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Zinc |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1315 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Wheat |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1310 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Genes |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
3563 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Cong Zhao |
| 9 (RLIN) |
26839 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mengjing Sun |
| 9 (RLIN) |
19597 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Luping Fu |
| 9 (RLIN) |
5903 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Jie Song |
| 9 (RLIN) |
19337 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Dan Liu |
| 9 (RLIN) |
19678 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Yelun Zhang |
| 9 (RLIN) |
1855 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Jianmin Zheng |
| 9 (RLIN) |
26840 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Zongjun Pu |
| 9 (RLIN) |
19742 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Lianzheng Liu |
| 9 (RLIN) |
26841 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Awais Rasheed |
| Miscellaneous information |
Global Wheat Program |
| Field link and sequence number |
I1706474 |
| 9 (RLIN) |
1938 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ming Li |
| 9 (RLIN) |
14174 |
| 700 0# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Xianchun Xia |
| 9 (RLIN) |
377 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
He Zhonghu |
| 9 (RLIN) |
838 |
| Miscellaneous information |
Global Wheat Program |
| Field link and sequence number |
INT2411 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Yuanfeng Hao |
| 9 (RLIN) |
919 |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Frontiers in Plant Science |
| Place, publisher, and date of publication |
Switzerland : Frontiers, 2022 |
| International Standard Serial Number |
1664-462X |
| Related parts |
v. 13, art. 840614 |
| Record control number |
56875 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Link text |
Open Access through DSpace |
| Uniform Resource Identifier |
https://hdl.handle.net/10883/22021 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Article |
| Suppress in OPAC |
No |
| Source of classification or shelving scheme |
Dewey Decimal Classification |