MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03279nab|a22004577a|4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
63448 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
MX-TxCIM |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20231017232120.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
202001s2021||||xxk|||p|op||||00||0|eng|d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
|---|
| International Standard Serial Number |
0960-7412 |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
|---|
| International Standard Serial Number |
1365-313X (Online) |
| 024 8# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
https://doi.org/10.1111/tpj.15147 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
MX-TxCIM |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Schaart, J.G. |
| 9 (RLIN) |
18936 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Exploring the alpha-gliadin locus : |
| Remainder of title |
the 33-mer peptide with six overlapping coeliac disease epitopes in Triticum aestivum is derived from a subgroup of Aegilops tauschii |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Name of publisher, distributor, etc. |
Wiley, |
| Date of publication, distribution, etc. |
2021. |
| Place of publication, distribution, etc. |
Oxford (United Kingdom) : |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Peer review |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Open Access |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Most alpha-gliadin genes of the Gli-D2 locus on the D genome of hexaploid bread wheat (Triticum aestivum) encode for proteins with epitopes that can trigger coeliac disease (CD), and several contain a 33-mer peptide with six partly overlapping copies of three epitopes, which is regarded as a remarkably potent T-cell stimulator. To increase genetic diversity in the D genome, synthetic hexaploid wheat lines are being made by hybridising accessions of Triticum turgidum (AB genome) and Aegilops tauschii (the progenitor of the D genome). The diversity of alpha-gliadins in A. tauschii has not been studied extensively. We analysed the alpha-gliadin transcriptome of 51 A. tauschii accessions representative of the diversity in A. tauschii. We extracted RNA from developing seeds and performed 454 amplicon sequencing of the first part of the alpha-gliadin genes. The expression profile of allelic variants of the alpha-gliadins was different between accessions, and also between accessions of the Western and Eastern clades of A. tauschii. Generally, both clades expressed many allelic variants not found in bread wheat. In contrast to earlier studies, we detected the 33-mer peptide in some A. tauschii accessions, indicating that it was introduced along with the D genome into bread wheat. In these accessions, transcripts with the 33-mer peptide were present at lower frequencies than in bread wheat varieties. In most A. tauschii accessions, however, the alpha-gliadins do not contain the epitope, and this may be exploited, through synthetic hexaploid wheats, to breed bread wheat varieties with fewer or no coeliac disease epitopes. |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
Text in English |
| 591 ## - CATALOGING NOTES |
|---|
| Affiliation |
Bentley, A.R. : No CIMMYT Affiliation |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Genomes |
| Miscellaneous information |
AGROVOC |
| Source of heading or term |
|
| 9 (RLIN) |
1131 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Gluten |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1974 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Gliadin |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
9085 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Soft wheat |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1265 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
T-lymphocytes |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
12417 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Aegilops |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1000 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Triticum aestivum |
| Source of heading or term |
AGROVOC |
| 9 (RLIN) |
1296 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Salentijn, E.M.J. |
| 9 (RLIN) |
18937 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Goryunova, S.V. |
| 9 (RLIN) |
18938 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Chidzanga, C. |
| 9 (RLIN) |
18939 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Esselink, D.G. |
| 9 (RLIN) |
18940 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Gosman, N. |
| 9 (RLIN) |
18941 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Bentley, A.R. |
| Field link and sequence number |
001712492 |
| Miscellaneous information |
Formerly Global Wheat Program |
| 9 (RLIN) |
9599 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Gilissen, L.J.W.J. |
| 9 (RLIN) |
18942 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Smulders, M.J.M. |
| 9 (RLIN) |
18943 |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Plant Journal |
| Place, publisher, and date of publication |
Oxford (United Kingdom) : Wiley, 2021. |
| International Standard Serial Number |
1365-313X |
| Related parts |
v. 106, no. 1, p. 86-94 |
| Record control number |
Gu444872 |
| 856 4# - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
https://doi.org/10.1111/tpj.15147 |
| Link text |
Click here to access online |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Article |
| Suppress in OPAC |
No |
| Source of classification or shelving scheme |
Dewey Decimal Classification |