Evaluation on reprogramed biological processes in transgenic maize varieties using transcriptomics and metabolomics (Record no. 63365)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02967nab|a22003737a|4500 |
| 001 - CONTROL NUMBER | |
| control field | 63365 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-TxCIM |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20211006085223.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201209s2021||||xxk|||p|op||||00||0|eng|d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 2045-2322 |
| 024 8# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | https://doi.org/10.1038/s41598-021-81637-2 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MX-TxCIM |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Wei Fu |
| 9 (RLIN) | 18614 |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation on reprogramed biological processes in transgenic maize varieties using transcriptomics and metabolomics |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | London (United Kingdom) : |
| Name of publisher, distributor, etc. | Nature Publishing Group, |
| Date of publication, distribution, etc. | 2021. |
| 500 ## - GENERAL NOTE | |
| General note | Peer review |
| 500 ## - GENERAL NOTE | |
| General note | Open Access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Genetic engineering (GM) has great potential to improve maize productivity, but rises some concerns on unintended effects, and equivalent as their comparators. There are some limitations through targeted analysis to detect the UE in genetically modified organisms in many previous studies. We here reported a case-study on the effects of introducing herbicides and insect resistance (HIR) gene cassette on molecular profiling (transcripts and metabolites) in a popular maize variety Zhengdan958 (ZD958) in China. We found that introducing HIR gene cassette bring a limited numbers of differential abundant genes (DAGs) or differential abundant metabolites (DAMs) between transgenic events and non-transgenic control. In contrast, averaged 10 times more DAGs and DAMs were observed when performed comparison under different growing environments in three different ecological regions of China than the numbers induced by gene effects. Major biological pathways relating to stress response or signaling transduction could explain somehow the effects of growing environments. We further compared two transgenic events mediated ZD958 (GM-ZD958) with either transgenic parent GM-Z58, and other genetic background nonGM-Z58, nonGM-ZD958, and Chang7-2. We found that the numbers of DAGs and DAMs between GM-ZD958 and its one parent maize variety, Z58 or GM-Z58 is equivalent, but not Chang7-2. These findings suggest that greater effects due to different genetic background on altered molecular profiling than gene modification itself. This study provides a case evidence indicating marginal effects of gene pleiotropic effects, and environmental effects should be emphasized. |
| 546 ## - LANGUAGE NOTE | |
| Language note | Text in English |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Transgenic plants |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 4329 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Maize |
| Miscellaneous information | AGROVOC |
| Source of heading or term | |
| 9 (RLIN) | 1173 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Plant biotechnology |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 8056 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Genetic engineering |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 8831 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pengyu Zhu |
| 9 (RLIN) | 18615 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mingnan Qu |
| 9 (RLIN) | 18616 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhi Wang |
| 9 (RLIN) | 18606 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yongjiang Zhang |
| 9 (RLIN) | 18617 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Feiwu Li |
| 9 (RLIN) | 18618 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shuifang Zhu |
| 9 (RLIN) | 18619 |
| 773 0# - HOST ITEM ENTRY | |
| Related parts | v. 11, art. 2050 |
| Place, publisher, and date of publication | London (United Kingdom) : Nature Publishing Group, 2021. |
| International Standard Serial Number | 2045-2322 |
| Title | Nature Scientific Reports |
| Record control number | a58025 |
| 856 4# - ELECTRONIC LOCATION AND ACCESS | |
| Link text | Click here to access online |
| Uniform Resource Identifier | https://doi.org/10.1038/s41598-021-81637-2 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Article |
| Suppress in OPAC | No |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Date last seen | Total Checkouts | Price effective from | Koha item type | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Withdrawn status | Home library | Current library | Date acquired |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 02/18/2021 | 02/18/2021 | Article | Not Lost | Dewey Decimal Classification | Reprints Collection | CIMMYT Knowledge Center: John Woolston Library | CIMMYT Knowledge Center: John Woolston Library | 02/18/2021 |