Metabolite‐based genome‐wide association study enables dissection of the flavonoid decoration pathway of wheat kernels (Record no. 62496)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02625nab a22004457a 4500 |
| 001 - CONTROL NUMBER | |
| control field | 62496 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-TxCIM |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20211006082419.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200212s2020 xxk|||p|op||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1467-7644 |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1467-7652 (Online) |
| 024 8# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | https://doi.org/10.1111/pbi.13335 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MX-TxCIM |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 8340 |
| Personal name | Jie Chen |
| 245 10 - TITLE STATEMENT | |
| Title | Metabolite‐based genome‐wide association study enables dissection of the flavonoid decoration pathway of wheat kernels |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | Oxford (United Kingdom) : |
| Name of publisher, distributor, etc. | Wiley, |
| Date of publication, distribution, etc. | 2020. |
| 500 ## - GENERAL NOTE | |
| General note | Peer review |
| 500 ## - GENERAL NOTE | |
| General note | Open Access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The marriage of metabolomic approaches with genetic design has proven a powerful tool in dissecting diversity in the metabolome and has additionally enhanced our understanding of complex traits. That said, such studies have rarely been carried out in wheat. In this study, we detected 805 metabolites from wheat kernels and profiled their relative contents among 182 wheat accessions, conducting a metabolite‐based genome‐wide association study (mGWAS) utilizing 14 646 previously described polymorphic SNP markers. A total of 1098 mGWAS associations were detected with large effects, within which 26 candidate genes were tentatively designated for 42 loci. Enzymatic assay of two candidates indicated they could catalyse glucosylation and subsequent malonylation of various flavonoids and thereby the major flavonoid decoration pathway of wheat kernel was dissected. Moreover, numerous high‐confidence genes associated with metabolite contents have been provided, as well as more subdivided metabolite networks which are yet to be explored within our data. These combined efforts presented the first step towards realizing metabolomics‐associated breeding of wheat. |
| 526 ## - STUDY PROGRAM INFORMATION NOTE | |
| Program name | Wheat CRP |
| 546 ## - LANGUAGE NOTE | |
| Language note | Text in English |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 12884 |
| Topical term or geographic name as entry element | Flavonoids |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 8948 |
| Topical term or geographic name as entry element | Metabolites |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Wheat |
| Miscellaneous information | AGROVOC |
| Source of heading or term | |
| 9 (RLIN) | 1310 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Source of heading or term | AGROVOC |
| 9 (RLIN) | 1168 |
| Topical term or geographic name as entry element | Kernels |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15512 |
| Personal name | Xin Hu |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 8341 |
| Personal name | Taotao Shi |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15513 |
| Personal name | Huanran Yin |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 8343 |
| Personal name | Dongfa Sun |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 919 |
| Personal name | Yuanfeng Hao |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 377 |
| Personal name | Xianchun Xia |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15514 |
| Personal name | Jie Luo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 2019 |
| Personal name | Fernie, A.R. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | He Zhonghu |
| Miscellaneous information | Global Wheat Program |
| Field link and sequence number | INT2411 |
| 9 (RLIN) | 838 |
| 700 0# - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 2613 |
| Personal name | Wei Chen |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | Oxford (United Kingdom) : Wiley, 2020. |
| Related parts | v. 18, no. 8, p. 1722-1735 |
| Title | Plant Biotechnology Journal |
| International Standard Serial Number | 1467-7652 |
| Record control number | u57523 |
| 856 4# - ELECTRONIC LOCATION AND ACCESS | |
| Link text | Open Access through DSpace |
| Uniform Resource Identifier | https://hdl.handle.net/10883/20943 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Article |
| Suppress in OPAC | No |
| Date last seen | Total Checkouts | Price effective from | Koha item type | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Withdrawn status | Home library | Current library | Date acquired |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 08/31/2020 | 08/31/2020 | Article | Not Lost | Dewey Decimal Classification | CIMMYT Staff Publications Collection | CIMMYT Knowledge Center: John Woolston Library | CIMMYT Knowledge Center: John Woolston Library | 08/31/2020 |